Dynamic changes in cervical glycosaminoglycan composition during normal pregnancy and preterm birth

Y Akgul, R Holt, M Mummert, A Word… - …, 2012 - academic.oup.com
Glycosaminoglycans (GAG) have diverse functions that regulate macromolecular assembly
in the extracellular matrix. During pregnancy, the rigid cervix transforms to a pliable structure …

[HTML][HTML] A new biological marker candidate in female reproductive system diseases: Matrix metalloproteinase with thrombospondin motifs (ADAMTS)

K Demircan, İ Cömertoğlu, S Akyol… - Journal of the Turkish …, 2014 - ncbi.nlm.nih.gov
Playing a key role in the pathophysiology of many diseases, A Disintegrin-like and
Metalloproteinase with Thrombospondin type-1 motif (ADAMTS) proteinases have been …

Transient role of the middle ear as a lower jaw support across mammals

N Anthwal, JC Fenelon, SD Johnston, MB Renfree… - Elife, 2020 - elifesciences.org
Mammals articulate their jaws using a novel joint between the dentary and squamosal
bones. In eutherian mammals, this joint forms in the embryo, supporting feeding and …

The platelet-derived growth factor receptor/STAT3 signaling pathway regulates the phenotypic transition of corpus cavernosum smooth muscle in rats

JF Yan, WJ Huang, JF Zhao, HY Fu, GY Zhang… - PLoS …, 2017 - journals.plos.org
Erectile dysfunction (ED) is a common clinical disease that is difficult to treat. We previously
found that hypoxia modulates the phenotype of primary corpus cavernosum smooth muscle …

Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-β1-mediated type I collagen …

L Xu, L Li, P Zhao, L Qi, P Li, J Gao… - Journal of Pharmacy and …, 2014 - academic.oup.com
Objective This study was to explore the antifibrotic effect and the possible mechanism of total
polysaccharides of Yupingfeng (YPF-P) on bleomycin (BLM)-induced pulmonary fibrosis in …

Phenotypic transition of corpus cavernosum smooth muscle cells subjected to hypoxia

B Lv, J Zhao, F Yang, X Huang, G Chen, K Yang… - Cell and tissue …, 2014 - Springer
Corpora cavernosum smooth muscle cells (CCSMCs) have been shown to play a critical
role in the male erectile response and are involved in the pathogenesis of multiple causes of …

Development of scaffold-free elastic cartilaginous constructs with structural similarities to auricular cartilage

R Giardini-Rosa, PP Joazeiro, K Thomas… - … Engineering Part A, 2014 - liebertpub.com
External ear reconstruction with autologous cartilage still remains one of the most difficult
problems in the fields of plastic and reconstructive surgery. As the absence of tissue …

Elastic fiber assembly in the adult mouse pubic symphysis during pregnancy and postpartum

SR Consonni, CC Werneck, DR Sobreira… - Biology of …, 2012 - academic.oup.com
Impairment of pelvic organ support has been described in mice with genetic modifications of
the proteins involved in elastogenesis, such as lysyl oxidase-like 1 (LOXL1) and fibulin 5 …

Time-dependent regulation of morphological changes and cartilage differentiation markers in the mouse pubic symphysis during pregnancy and postpartum recovery

BG Castelucci, SR Consonni, VS Rosa, LA Sensiate… - PLoS …, 2018 - journals.plos.org
Animal models commonly serve as a bridge between in vitro experiments and clinical
applications; however, few physiological processes in adult animals are sufficient to serve …

High iNOS mRNA and protein localization during late pregnancy suggest a role for nitric oxide in mouse pubic symphysis relaxation

CF Moro, SR Consonni, RG Rosa… - Molecular …, 2012 - Wiley Online Library
Remodeling and relaxation of the mouse pubic symphysis (PS) are central events in
parturition. The mouse PS remodels in a hormone‐controlled process that involves the …