The role of microRNAs in the pathophysiology of human central nervous system: a focus on neurodegenerative diseases
Abstract microRNAs (miRNAs) are suggested to play substantial roles in regulating the
development and various physiologic functions of the central nervous system (CNS). These …
development and various physiologic functions of the central nervous system (CNS). These …
The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
E Mogilyansky, I Rigoutsos - Cell Death & Differentiation, 2013 - nature.com
Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …
cluster and its members has been increasing steadily and the number of publications has …
Circular RNAs are a large class of animal RNAs with regulatory potency
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function.
To explore circRNAs systematically, we sequenced and computationally analysed human …
To explore circRNAs systematically, we sequenced and computationally analysed human …
MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates
J Hordeaux, EL Buza, B Jeffrey, C Song… - Science translational …, 2020 - science.org
Delivering adeno-associated virus (AAV) vectors into the central nervous system of
nonhuman primates (NHPs) via the blood or cerebral spinal fluid is associated with dorsal …
nonhuman primates (NHPs) via the blood or cerebral spinal fluid is associated with dorsal …
Neurogenesis in the embryonic and adult brain: same regulators, different roles
N Urbán, F Guillemot - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic
niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological …
niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological …
Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome …
To test, in vivo, the hypothesis that exosomes from multipotent mesenchymal stromal cells
(MSCs) mediate microRNA 133b (miR-133b) transfer which promotes neurological recovery …
(MSCs) mediate microRNA 133b (miR-133b) transfer which promotes neurological recovery …
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU. 1 pathway
ED Ponomarev, T Veremeyko, N Barteneva… - Nature medicine, 2011 - nature.com
MicroRNAs are a family of regulatory molecules involved in many physiological processes,
including differentiation and activation of cells of the immune system. We found that brain …
including differentiation and activation of cells of the immune system. We found that brain …
Competing endogenous RNAs (ceRNAs): new entrants to the intricacies of gene regulation
RV Kartha, S Subramanian - Frontiers in genetics, 2014 - frontiersin.org
The discovery of microRNAs (miRNAs) has led to a paradigm shift in our basic
understanding of gene regulation. Competing endogenous RNAs (ceRNAs) are the recent …
understanding of gene regulation. Competing endogenous RNAs (ceRNAs) are the recent …
Exosomes/miRNAs as mediating cell-based therapy of stroke
Cell-based therapy, eg, multipotent mesenchymal stromal cell (MSC) treatment, shows
promise for the treatment of various diseases. The strong paracrine capacity of these cells …
promise for the treatment of various diseases. The strong paracrine capacity of these cells …