Aspects of point-of-care diagnostics for personalized health wellness

S Kumar, M Nehra, S Khurana, N Dilbaghi… - International journal …, 2021 - Taylor & Francis
Advancements in analytical diagnostic systems for point-of-care (POC) application have
gained considerable attention because of their rapid operation at the site required to …

Diagnostics of Ebola virus

A Bettini, D Lapa, AR Garbuglia - Frontiers in Public Health, 2023 - frontiersin.org
Ebola is a highly pathogenic virus, which in humans reaches a mortality rate above 50%.
Due to a lack of laboratories in territories where Ebola viruses are endemic and the limited …

[HTML][HTML] Monoclonal antibody therapy for Ebola virus disease

MM Levine - New England Journal of Medicine, 2019 - Mass Medical Soc
Early reports in 1976 and 1995 documented cases in the Democratic Republic of Congo
(DRC) of what we now know to be Ebola virus disease (EVD) caused by Zaire ebolavirus …

Field performance of three Ebola rapid diagnostic tests used during the 2018–20 outbreak in the eastern Democratic Republic of the Congo: a retrospective …

D Mukadi-Bamuleka, J Bulabula-Penge… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background The Democratic Republic of the Congo has confronted 13 outbreaks
of Ebola virus disease since 1976. Rapid diagnostic tests (RDTs) detecting viral antigens …

Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR

CM Fontes, BD Lipes, J Liu, KN Agans, A Yan… - Science translational …, 2021 - science.org
Ebola virus (EBOV) hemorrhagic fever outbreaks have been challenging to deter due to the
lack of health care infrastructure in disease-endemic countries and a corresponding inability …

Treatment of Ebola-related critical illness

P Kiiza, S Mullin, K Teo, NKJ Adhikari… - Intensive care medicine, 2020 - Springer
Purpose To explore contemporary clincial case management of patients with Ebola virus
disease. Methods A narrative review from a clinical perspective of clinical features …

Head-to-head comparison of diagnostic accuracy of four Ebola virus disease rapid diagnostic tests versus GeneXpert® in eastern Democratic Republic of the Congo …

D Mukadi-Bamuleka, J Bulabula-Penge… - …, 2023 - thelancet.com
Background Ebola virus disease (EVD) outbreaks have emerged in Central and West Africa.
EVD diagnosis relies principally on RT-PCR testing with GeneXpert®, which has logistical …

[HTML][HTML] Non-Ebola filoviruses: potential threats to global health security

Y Munyeku-Bazitama, F Edidi-Atani, A Takada - Viruses, 2024 - mdpi.com
Filoviruses are negative-sense single-stranded RNA viruses often associated with severe
and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality …

[HTML][HTML] Rapid diagnostic tests versus RT–PCR for Ebola virus infections: a systematic review and meta-analysis

BA Muzembo, K Kitahara, A Ohno… - Bulletin of the World …, 2022 - ncbi.nlm.nih.gov
Objective To evaluate the clinical accuracy of rapid diagnostic tests for the detection of Ebola
virus. Methods We searched MEDLINE®, Embase® and Web of Science for articles …

Cost-effectiveness of incorporating Ebola prediction score tools and rapid diagnostic tests into a screening algorithm: A decision analytic model

AO Tshomba, D Mukadi-Bamuleka, A De Weggheleire… - Plos one, 2023 - journals.plos.org
Background No distinctive clinical signs of Ebola virus disease (EVD) have prompted the
development of rapid screening tools or called for a new approach to screening suspected …