Aging of cerebral white matter

H Liu, Y Yang, Y Xia, W Zhu, RK Leak, Z Wei… - Ageing research …, 2017 - Elsevier
White matter (WM) occupies a large volume of the human cerebrum and is mainly composed
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …

Parkinson's disease: from synaptic loss to connectome dysfunction

A Bellucci, NB Mercuri, A Venneri… - Neuropathology and …, 2016 - Wiley Online Library
Parkinson's disease (PD) is a common neurodegenerative disorder with prominent loss of
nigro‐striatal dopaminergic neurons. The resultant dopamine (DA) deficiency underlies the …

Postural instability in Parkinson's disease: a review

B Palakurthi, SP Burugupally - Brain sciences, 2019 - mdpi.com
Parkinson's disease (PD) is a heterogeneous progressive neurodegenerative disorder,
which typically affects older adults; it is predicted that by 2030 about 3% of the world …

Multifunctional role of natural products for the treatment of Parkinson's disease: at a glance

MM Rahman, X Wang, MR Islam, S Akash… - Frontiers in …, 2022 - frontiersin.org
Natural substances originating from plants have long been used to treat neurodegenerative
disorders (NDs). Parkinson's disease (PD) is a ND. The deterioration and subsequent …

Vitamin B12 and homocysteine levels predict different outcomes in early Parkinson's disease

CW Christine, P Auinger, A Joslin… - Movement …, 2018 - Wiley Online Library
ABSTRACT Background: In moderately advanced Parkinson's disease (PD), low serum
vitamin B12 levels are common and are associated with neuropathy and cognitive …

Diffusion alterations associated with Parkinson's disease symptomatology: a review of the literature

JM Hall, KAE Martens, CC Walton… - Parkinsonism & Related …, 2016 - Elsevier
Parkinson's disease (PD) is a heterogeneous neurological disorder with a variety of motor
and non-motor symptoms. The underlying mechanisms of these symptoms are not fully …

The potential role of herbal products in the treatment of Parkinson's disease

MS Amro, SL Teoh, AG Norzana… - La Clinica Terapeutica, 2018 - clinicaterapeutica.it
Parkinson's disease (PD) is a multifactorial disorder of the nervous system in which there is
a progressive loss of dopaminergic neurons. There is a disturbance in the movement in PD …

Neuroimaging detectable differences between Parkinson's disease motor subtypes: a systematic review

JT Boonstra, S Michielse, Y Temel… - Movement disorders …, 2021 - Wiley Online Library
Background The neuroanatomical substrates of Parkinson's disease (PD) with tremor‐
dominance (TD) and those with non‐tremor dominance (nTD), postural instability and gait …

Brain imaging of locomotion in neurological conditions

G Allali, HM Blumen, H Devanne, E Pirondini… - Neurophysiologie …, 2018 - Elsevier
Impaired locomotion is a frequent and major source of disability in patients with neurological
conditions. Different neuroimaging methods have been used to understand the brain …

Different patterns of spontaneous brain activity between tremor‐dominant and postural instability/gait difficulty subtypes of Parkinson's disease: a resting‐state fMRI …

HM Chen, ZJ Wang, JP Fang, LY Gao… - CNS neuroscience & …, 2015 - Wiley Online Library
Aims Postural instability/gait difficulty (PIGD) and tremor‐dominant (TD) subtypes of
Parkinson's disease (PD) show different clinical manifestations; however, their underlying …