The gut microbiota as a target to control hyperuricemia pathogenesis: Potential mechanisms and therapeutic strategies

J Wang, Y Chen, H Zhong, F Chen… - Critical Reviews in …, 2022 - Taylor & Francis
Hyperuricemia (HUA) is a metabolic disorder caused by abnormal uric acid (UA)
metabolism, which is a complex physiological process involving multiple organs (liver …

Prevalence of hyperuricemia and gout in mainland China from 2000 to 2014: a systematic review and meta‐analysis

R Liu, C Han, D Wu, X Xia, J Gu, H Guan… - BioMed research …, 2015 - Wiley Online Library
We systematically identified the prevalence of hyperuricemia and gout in mainland China
and provided informative data that can be used to create appropriate local public health …

[HTML][HTML] The role of xanthine oxidoreductase and uric acid in metabolic syndrome

MG Battelli, M Bortolotti, L Polito, A Bolognesi - Biochimica et Biophysica …, 2018 - Elsevier
Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome
through the oxidative stress and the inflammatory response induced by XOR-derived …

Disorders of lipid metabolism in chronic kidney disease

MC Bulbul, T Dagel, B Afsar, NN Ulusu, M Kuwabara… - Blood purification, 2018 - karger.com
Cardiovascular disease (CVD) is the leading cause of death in chronic kidney disease
(CKD). One of the most important pathophysiological mechanisms for CVD in patients with …

The relationship between serum uric acid and lipid profile in Bangladeshi adults

N Ali, S Rahman, S Islam, T Haque, NH Molla… - BMC cardiovascular …, 2019 - Springer
Background Although the link between elevated uric acid and metabolic syndrome has been
reported in some studies; the relationship of serum uric acid (SUA) with lipid profile has not …

[HTML][HTML] Serum uric acid to HDL-cholesterol ratio is a strong predictor of metabolic syndrome in type 2 diabetes mellitus

MZ Kocak, G Aktas, E Erkus, I Sincer, B Atak… - Revista da Associação …, 2019 - SciELO Brasil
SUMMARY OBJECTIVE Metabolic syndrome (MS) is a clinical entity that associated with
increased risk of type 2 Diabetes Mellitus (DM) and cardiovascular diseases. Serum uric …

Elevated serum uric acid increases risks for developing high LDL cholesterol and hypertriglyceridemia: A five-year cohort study in Japan

M Kuwabara, C Borghi, AFG Cicero, I Hisatome… - International journal of …, 2018 - Elsevier
Background High serum uric acid (SUA) is associated with the dyslipidemia, but whether
hyperuricemia predicts an increase in serum low-density lipoprotein (LDL) cholesterol is …

[HTML][HTML] Xanthine oxidoreductase: A leading actor in cardiovascular disease drama

L Polito, M Bortolotti, MG Battelli, A Bolognesi - Redox Biology, 2021 - Elsevier
Cardiovascular diseases (CVD) are the leading cause of global mortality and their
pathogenesis lies mainly in the atherosclerotic process. There are close connections linking …

Alterations of the gut microbiome associated with the treatment of hyperuricaemia in male rats

Y Yu, Q Liu, H Li, C Wen, Z He - Frontiers in microbiology, 2018 - frontiersin.org
Hyperuricaemia is an important risk factor for many diseases including gout, hypertension,
and type II diabetes. The gut microbiota is associated with hyperuricaemia and has also …

Association between blood metal exposures and hyperuricemia in the US general adult: A subgroup analysis from NHANES

Y Tan, Y Fu, F Huang, L Wen, X Weng, H Yao, H Liang… - Chemosphere, 2023 - Elsevier
Background The relationship between metal exposure and hyperuricemia is still
controversial, especially in certain population groups. Methods This cross-sectional study …