Beyond the TCA cycle: new insights into mitochondrial calcium regulation of oxidative phosphorylation

SH Lee, HE Duron, D Chaudhuri - Biochemical Society …, 2023 - portlandpress.com
While mitochondria oxidative phosphorylation is broadly regulated, the impact of
mitochondrial Ca2+ on substrate flux under both physiological and pathological conditions …

An update on the role of sex hormones in the function of the cardiorenal mitochondria

AS Shulha, V Shyshenko, RS Schibalski… - Biochemical Society …, 2024 - portlandpress.com
Multiple studies have highlighted the crucial role of mitochondrial bioenergetics in
understanding the progression of cardiorenal diseases, revealing new potential treatment …

Sex differences in cardiac energetics in the rat ventricular muscle

M Rahmani, T Pham, DJ Crossman, K Tran… - Scientific Reports, 2024 - nature.com
Cardiac sex-difference functional studies have centred on measurements of twitch force and
Ca2+ dynamics. The energy expenditures from these two cellular processes: activation …

Is androstadienone a human male pheromone? More research is needed

J Gan, Y Wu, X Lei, C Han - Physiology & behavior, 2024 - Elsevier
Abstract Androsta-4, 16-dien-3-one (androstadienone, AND), a steroid predominantly found
in male secretions, has been associated with a variety of sex-specific effects on emotion …

Calpain inhibition decreases oxidative stress via mitochondrial regulation in a swine model of chronic myocardial ischemia

BA Potz, SA Sabe, LA Scrimgeour, AA Sabe… - Free Radical Biology …, 2023 - Elsevier
Introduction Calpain overexpression is implicated in mitochondrial damage leading to tissue
oxidative stress and myocardial ischemic injury. The aim of this study was to determine the …

In Utero Nano-Titanium Dioxide Exposure Results in Sexually Dimorphic Weight Gain and Cardiovascular Function in Offspring

R Hunter, T Gluth, E Meadows, R Nett, V Nist… - Cardiovascular …, 2025 - Springer
Engineered nanomaterials (ENM) are capable of crossing the placental barrier and
accumulating in fetal tissue. Specifically, the ENM nano-titanium dioxide (nano-TiO 2), has …

Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia

Y Lai, F Loy, M Isola, R Noli, A Rinaldi, C Lobina… - Biomedicines, 2023 - mdpi.com
The use of hypoxic devices among athletes who train in normobaric hypoxia has become
increasingly popular; however, the acute effects on heart and brain metabolism are not yet …

Reduction in activity and abundance of mitochondrial electron transport chain supercomplexes in pulmonary hypertension-induced right ventricular dysfunction

W Ma, P Zhang, A Vang, A Zimmer, S Huck, P Nicely… - bioRxiv, 2024 - biorxiv.org
Pulmonary hypertension (PH) results in RV hypertrophy, fibrosis and dysfunction resulting in
RV failure which is associated with impaired RV metabolism and mitochondrial respiration …

Alteraciones metabólicas y comportamentales por la eliminación de la enzima proglucolítica PFKFB3 de astrocitos en ratón

P Alonso-Batán - 2023 - gredos.usal.es
[ES] El acoplamiento metabólico entre astrocitos y neuronas es crucial para un adecuado
funcionamiento cerebral y, por ende, para las funciones neurales superiores. La …