The design and engineering of synthetic genomes

JS James, J Dai, WL Chew, Y Cai - Nature Reviews Genetics, 2024 - nature.com
Synthetic genomics seeks to design and construct entire genomes to mechanistically dissect
fundamental questions of genome function and to engineer organisms for diverse …

Genetic code robustness and protein evolvability are correlated and protein-specific

BPH Metzger - Plos Biology, 2024 - journals.plos.org
The relationship between genetic code robustness and protein evolvability is unknown. A
new study in PLOS Biology using in silico rewiring of genetic codes and functional protein …

[PDF][PDF] Adaptive Landscapes Across Multiple Scales

M Srivastava - 2024 - research-collection.ethz.ch
Visualizing evolution as a hill-climbing process on an adaptive landscape–which maps
genotypes to their reproductive capability or fitness–has emerged as a valuable tool for …