Abstract Fibrous Dysplasia/McCune Albright syndrome (FD/MAS) represents a wide
spectrum of diseases due to somatic gain-of-function mutations of the GNAS gene. The …

Abstract Fibrous dysplasia/McCune-Albright syndrome (FD/MAS) is a rare disorder of
striking complexity. It arises from somatic, gain-of-function mutations in GNAS, leading to …

This volume covers tumors of the pituary, the thyroid and parathyroid, the adrenal gland, the
endocrine pancreas, and inherited tumor syndromes. Each entity is extensively discussed …

McCune-Albright syndrome (MAS) is classically defined by the clinical triad of fibrous
dysplasia of bone (FD), café-au-lait skin spots, and precocious puberty (PP). It is a rare …

Context: Cabergoline is widely considered to be poorly effective in acromegaly. Objective:
The aim of this study was to obtain a more accurate picture of the efficacy of cabergoline in …

Fibrous dysplasia (FD) is sometimes accompanied by extraskeletal manifestations that can
include any combination of café-au-lait macules, hyperfunctioning endocrinopathies, such …

Background: McCune-Albright syndrome (MAS) includes the triad of poly/monostotic fibrous
dysplasia, café-au-lait spots, and hyperfunctioning endocrinopathies. Acromegaly affects …

The genetic landscape of pituitary adenomas (PAs) is diverse and many of the identified
cases remain of unclear pathogenetic mechanism. Germline genetic defects account for a …

A multicenter study on fibrous dysplasia of bone (FD) was promoted by the European
Pediatric Orthopaedic Society in 1999 in order to gain insight into the natural history of the …

In patients with polyostotic fibrous dysplasia of bone, the peak incidence of fractures is
during the first decade of life, followed by a decrease thereafter. Phosphaturia is associated …