Differentiation of osteoblasts: the links between essential transcription factors

J Khotib, HD Marhaeny, A Miatmoko… - Journal of …, 2023 - Taylor & Francis
Osteoblasts, cells derived from mesenchymal stem cells (MSCs) in the bone marrow, are
cells responsible for bone formation and remodeling. The differentiation of osteoblasts from …

[HTML][HTML] Research progress of gene therapy combined with tissue engineering to promote bone regeneration

X Chu, Y Xiong, L Lu, Y Wang, J Wang, R Zeng… - APL …, 2024 - pubs.aip.org
Gene therapy has emerged as a highly promising strategy for the clinical treatment of large
segmental bone defects and non-union fractures, which is a common clinical need …

A porous hydrogel with high mechanical strength and biocompatibility for bone tissue engineering

C Xiang, X Zhang, J Zhang, W Chen, X Li… - Journal of Functional …, 2022 - mdpi.com
Polyvinyl alcohol (PVA) hydrogels are considered to be ideal materials for tissue
engineering due to their high water content, low frictional behavior, and good …

[HTML][HTML] Osteoinduction-immunomodulation dual-functional calcium nervonate nanoparticles for promoting bone regeneration

W Ma, W Wang, F Liu, Y Kong, B Xia, H Yang… - Composites Part B …, 2023 - Elsevier
Stem cell-based bone repair in vivo relies on both the osteogenic differentiation of stem cells
and the immune activities of immune cells. The lack of effective means to simultaneously …

[HTML][HTML] Myc-mediated circular RNA circMcph1/miR-370-3p/Irak2 axis is a progressive regulator in hepatic fibrosis

JJ Xu, X Chen, S Zhu, LF Jiang, WX Ma, SY Chen… - Life Sciences, 2023 - Elsevier
Aims Treating hepatic fibrosis (HF) is a major challenge worldwide. However, the biological
functions and regulatory mechanisms of circular RNAs (circRNAs) remain unclear in HF. The …

ALKBH5 Regulates Osteogenic Differentiation via the lncRNA/mRNA Complex

Y Song, H Gao, Y Pan, Y Gu, W Sun… - Journal of dental …, 2024 - journals.sagepub.com
Human adipose-derived stem cells (hASCs) are commonly used in bone tissue
regeneration. The N6-methyladenosine (m6A) modification has emerged as a novel …

Circ‐ZNF236 mediates stem cells from apical papilla differentiation by regulating LGR4‐induced autophagy

Y Xiao, L Chen, Y Xu, R Yu, J Lu, Y Ke… - International …, 2024 - Wiley Online Library
Aim Human stem cells from the apical papilla (SCAPs) are an appealing stem cell source for
tissue regeneration engineering. Circular RNAs (circRNAs) are known to exert pivotal …

hsa_circ_0001599 promotes odontogenic differentiation of human dental pulp stem cells by increasing ITGA2 expression and stability

Y Yang, C Jiang, J Zeng, X Guo, M Chen… - Communications …, 2025 - nature.com
Dental pulp regeneration is significantly aided by human dental pulp stem cells (hDPSCs).
An increasing number of studies have demonstrated that circular RNAs (circRNAs) are …

Tailoring adipose stem cells towards high therapeutic performance: Perspectives in manipulation and manufacturing

J Song, L Zhang, B Song, G Yang - Chemical Engineering Journal, 2023 - Elsevier
Adipose tissues are broadly distributed in human bodies especially of the obese population,
which have long been considered as a surplus proportion. With the advancement of cell …

Differential expression profiles and functional prediction of circRNA in mice with traumatic heterotopic ossification

Z Wang, X Yi, Y Liu, Q Liu, Z Li, A Yu - Frontiers in Immunology, 2023 - frontiersin.org
Background Traumatic heterotopic ossification (HO) is an intractable sequela incited by
inflammatory insult. To date, the exact molecular mechanisms of traumatic HO formation …