Genomic assays for Epstein–Barr virus-positive gastric adenocarcinoma

ML Gulley - Experimental & molecular medicine, 2015 - nature.com
A small set of gastric adenocarcinomas (9%) harbor Epstein–Barr virus (EBV) DNA within
malignant cells, and the virus is not an innocent bystander but rather is intimately linked to …

[HTML][HTML] A majority of low (1-10%) ER positive breast cancers behave like hormone receptor negative tumors

JS Prabhu, A Korlimarla, K Desai, A Alexander… - Journal of …, 2014 - ncbi.nlm.nih.gov
Background: The 2010 guidelines by ASCO-CAP have mandated that breast cancer
specimens with≥ 1% positively staining cells by immunohistochemistry should be …

[HTML][HTML] An androgen receptor regulated gene score is associated with epithelial to mesenchymal transition features in triple negative breast cancers

S Rajarajan, VP Snijesh, CE Anupama, MG Nair… - Translational …, 2023 - Elsevier
Background Androgen receptor (AR) is considered a marker of better prognosis in hormone
receptor positive breast cancers (BC), however, its role in triple negative breast cancer …

Cystic neutrophilic granulomatous mastitis: a clinicopathological study with 16s rRNA sequencing for the detection of corynebacteria in formalin-fixed paraffin …

MA Naik, A Korlimarla, ST Shetty… - … journal of surgical …, 2020 - journals.sagepub.com
Cystic neutrophilic granulomatous mastitis (CNGM) is a histologically characterized variant
of granulomatous lobular mastitis that is associated with lipophilic Corynebacterium species …

miR‐18a activates Wnt pathway in ER‐positive breast cancer and is associated with poor prognosis

MG Nair, JS Prabhu, A Korlimarla, S Rajarajan… - Cancer …, 2020 - Wiley Online Library
Despite the established benefits of long‐term endocrine therapy, women with hormone
receptor‐positive breast cancer remain at risk for late relapse. The basis of this is multi …

miR-18a mediates immune evasion in ER-positive breast cancer through Wnt signaling

MG Nair, S VP, S Patil, A CE, G Mukherjee, RV Kumar… - Cells, 2022 - mdpi.com
ER-positive (ER+) breast cancer is considered immunologically 'silent'with fewer tumor-
infiltrating immune cells. We have previously demonstrated the role of miR-18a in mediating …

High expression of integrin β6 in association with the Rho–Rac pathway identifies a poor prognostic subgroup within HER2 amplified breast cancers

K Desai, MG Nair, JS Prabhu, A Vinod… - Cancer …, 2016 - Wiley Online Library
Integrin αvβ6 is involved in the transition from ductal carcinoma in situ (DCIS) to invasive
ductal carcinoma (IDC) of the breast. In addition, integrin β6 (ITGB 6) is of prognostic value …

Placental expression of angiogenesis-related genes and their receptors in IUGR pregnancies: correlation with fetoplacental and maternal parameters

G Ravikumar, A Mukhopadhyay, C Mani… - The Journal of …, 2020 - Taylor & Francis
Objectives: Aberrations in placental vascular development compromising fetal supply of
oxygen and essential nutrients can be a significant contributor to intrauterine growth …

β3 integrin promotes chemoresistance to epirubicin in MDA-MB-231 through repression of the pro-apoptotic protein, BAD

MG Nair, K Desai, JS Prabhu, PS Hari… - Experimental Cell …, 2016 - Elsevier
Resistance to anthracycline based chemotherapy is a major limitation in the treatment of
breast cancer, particularly of the triple negative sub-type that lacks targeted therapies …

[HTML][HTML] Comprehensive characterization of immune landscape of Indian and Western triple negative breast cancers

A Korlimarla, PS Hari, J Prabhu, C Ragulan, Y Patil… - Translational …, 2022 - Elsevier
Purpose Triple-negative breast cancer (TNBC) is a heterogeneous disease with a significant
challenge to effectively manage in the clinic worldwide. Immunotherapy may be beneficial to …