Thiazoles, their benzofused systems, and thiazolidinone derivatives: versatile and promising tools to combat antibiotic resistance
S Cascioferro, B Parrino, D Carbone… - Journal of medicinal …, 2020 - ACS Publications
Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized
as nuclei of great value for obtaining molecules with various biological activities, including …
as nuclei of great value for obtaining molecules with various biological activities, including …
Current Development of Thiazole-Containing Compounds as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus
H Liu, T Xu, Z Xue, M Huang, T Wang… - ACS Infectious …, 2024 - ACS Publications
The emergence of multi-drug-resistant bacteria is threatening to human health and life
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …
Design and synthesis of new spirooxindole candidates and their selenium nanoparticles as potential dual Topo I/II inhibitors, DNA intercalators, and apoptotic …
S El-Kalyoubi, MM Khalifa, MT Abo-Elfadl… - Journal of enzyme …, 2023 - Taylor & Francis
A new wave of dual Topo I/II inhibitors was designed and synthesised via the hybridisation
of spirooxindoles and pyrimidines. In situ selenium nanoparticles (SeNPs) for some …
of spirooxindoles and pyrimidines. In situ selenium nanoparticles (SeNPs) for some …
Recent advances in DNA gyrase-targeted antimicrobial agents
Antimicrobial resistance is one of the greatest challenges facing the world today. In the
United States alone, it is responsible for the death of more than 20,000 people each year …
United States alone, it is responsible for the death of more than 20,000 people each year …
[HTML][HTML] Antimicrobial, antiproliferative activities and molecular docking of metabolites from Alternaria alternata
Endophytic fungi allied to plants have sparked substantial promise in discovering new
bioactive compounds. In this study, propagation of the endophytic fungus Alternaria …
bioactive compounds. In this study, propagation of the endophytic fungus Alternaria …
Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation
LL Wang, N Battini, RRY Bheemanaboina… - European journal of …, 2019 - Elsevier
A series of aminothiazolyl norfloxacin analogues as a new type of potential antimicrobial
agents were synthesized and screened for their antimicrobial activities. Most of the prepared …
agents were synthesized and screened for their antimicrobial activities. Most of the prepared …
A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes …
LL Wang, N Battini, RRY Bheemanaboina… - European Journal of …, 2019 - Elsevier
This work did a new exploration towards aminothiazolquinolone oximes as potentially multi-
targeting antimicrobial agents. A class of novel hybrids of quinolone, aminothiazole …
targeting antimicrobial agents. A class of novel hybrids of quinolone, aminothiazole …
Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii
WW Gao, L Gopala, RRY Bheemanaboina… - European journal of …, 2018 - Elsevier
Aminothiazolyl berberine derivatives as potentially antimicrobial agents were designed and
synthesized in an effort to overcome drug resistance. The antimicrobial assay revealed that …
synthesized in an effort to overcome drug resistance. The antimicrobial assay revealed that …
Astaxanthin‐Mediated Bacterial Lethality: Evidence from Oxidative Stress Contribution and Molecular Dynamics Simulation
JO Aribisala, S Nkosi, K Idowu… - Oxidative medicine …, 2021 - Wiley Online Library
The involvement of cellular oxidative stress in antibacterial therapy has remained a topical
issue over the years. In this study, the contribution of oxidative stress to astaxanthin …
issue over the years. In this study, the contribution of oxidative stress to astaxanthin …
Identification of secondary metabolites from Crescentia cujete as promising antibacterial therapeutics targeting type 2A topoisomerases through molecular dynamics …
JO Aribisala, RA Abdulsalam, Y Dweba… - Computers in Biology …, 2022 - Elsevier
The potential of fluoroquinolones as remarkable antibacterial agents evolved from their
ability to generate 'poison'complexes between type IIA topoisomerases [topo2As (DNA …
ability to generate 'poison'complexes between type IIA topoisomerases [topo2As (DNA …