Treatment of spinal cord injury with mesenchymal stem cells

LL Liau, QH Looi, WC Chia, T Subramaniam, MH Ng… - Cell & bioscience, 2020 - Springer
Background Spinal cord injury (SCI) is the damage to the spinal cord that can lead to
temporary or permanent loss of function due to injury to the nerve. The SCI patients are often …

Paracrine mechanisms in adult stem cell signaling and therapy

M Gnecchi, Z Zhang, A Ni, VJ Dzau - Circulation research, 2008 - Am Heart Assoc
Animal and preliminary human studies of adult cell therapy following acute myocardial
infarction have shown an overall improvement of cardiac function. Myocardial and vascular …

[PDF][PDF] Bioactive silicate nanoplatelets for osteogenic differentiation of human mesenchymal stem cells

AK Gaharwar, SM Mihaila, A Swami, A Patel, S Sant… - Adv. Mater, 2013 - researchgate.net
With an aging US population, the occurrence of injuries and degenerative conditions are
subsequently on the rise. As a direct result, there is an increase in demand for therapies that …

Immunomodulatory properties of mesenchymal stromal cells

AJ Nauta, WE Fibbe - Blood, The Journal of the American …, 2007 - ashpublications.org
Mesenchymal stem cells (MSCs) are multipotential nonhematopoietic progenitor cells
capable of differentiating into multiple lineages of the mesenchyme. MSCs have emerged as …

Mesenchymal stem cell effects on T-cell effector pathways

MM Duffy, T Ritter, R Ceredig, MD Griffin - Stem cell research & therapy, 2011 - Springer
Mesenchymal stem (stromal) cells (MSCs) are rare, multipotent progenitor cells that can be
isolated and expanded from bone marrow and other tissues. Strikingly, MSCs modulate the …

Bioprinting functional tissues

AN Leberfinger, S Dinda, Y Wu, SV Koduru, V Ozbolat… - Acta biomaterialia, 2019 - Elsevier
Despite the numerous lives that have been saved since the first successful procedure in
1954, organ transplant has several shortcomings which prevent it from becoming a more …

Cell contact, prostaglandin E2 and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3 …

K English, JM Ryan, L Tobin, MJ Murphy… - Clinical & …, 2009 - academic.oup.com
Adult human mesenchymal stromal or stem cells (MSC) can differentiate into a variety of cell
types and are candidate cellular therapeutics in regenerative medicine. Surprisingly, these …

Mesenchymal stem cells avoid allogeneic rejection

JM Ryan, FP Barry, JM Murphy, BP Mahon - Journal of inflammation, 2005 - Springer
Adult bone marrow derived mesenchymal stem cells offer the potential to open a new
frontier in medicine. Regenerative medicine aims to replace effete cells in a broad range of …

Adipose-derived mesenchymal stem cells alleviate experimental colitis by inhibiting inflammatory and autoimmune responses

MA González, E Gonzalez–Rey, L Rico, D Büscher… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Crohn's disease is a chronic disease characterized by severe T-
helper (Th) 1 cell–driven inflammation of the colon partially caused by a loss of immune …

Immune properties of human umbilical cord Wharton's jelly-derived cells

ML Weiss, C Anderson, S Medicetty… - Stem …, 2008 - academic.oup.com
Cells isolated from Wharton's jelly, referred to as umbilical cord matrix stromal (UCMS) cells,
adhere to a tissue-culture plastic substrate, express mesenchymal stromal cell (MSC) …