Ca2+/calmodulin-dependent protein kinase kinase (CaMKK) is the activating kinase for
multiple downstream kinases, including CaM-kinase I (CaMKI), CaM-kinase IV (CaMKIV) …

Abstract In 2011, CAMKK2, the gene encoding calcium/calmodulin-dependent kinase
kinase 2 (CAMKK2), was demonstrated to be a direct target of the androgen receptor and a …

Previous work has suggested androgen receptor (AR) signaling mediates prostate cancer
progression in part through the modulation of autophagy. However, clinical trials testing …

Abstract The Pathogen Box is a 400‐strong collection of drug‐like compounds, selected for
their potential against several of the world's most important neglected tropical diseases …

Abstract Ca2+/CaM‐dependent protein kinase kinases 1 and 2 (CaMKK1 and CaMKK2)
phosphorylate and enhance the catalytic activity of downstream kinases CaMKI, CaMKIV …

CAMKK2 is a serine/threonine kinase and an activator of AMPK whose dysregulation is
linked with multiple diseases. Unfortunately, STO-609, the tool inhibitor commonly used to …

The calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) activates CAMK1,
CAMK4, AMPK, and AKT, leading to numerous physiological responses. The deregulation of …

The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2
(CAMKK2) plays critical roles in a range of biological processes. Despite its importance, only …

Despite early studies linking calcium-calmodulin protein kinase kinase 2 (CAMKK2) to
prostate cancer cell migration and invasion, the role of CAMKK2 in metastasis in vivo …

The significance of automated drug design using virtual generative models has steadily
grown in recent years. While deep learning-driven solutions have received growing …