Inherited retinal diseases (IRDs) cause progressive loss of light-sensitive photoreceptors in
the eye and can lead to blindness. Gene-based therapies for IRDs have shown remarkable …

Diabetic retinopathy (DR) is a universal microvascular complication of diabetes mellitus
(DM), which is the main reason for global sight damage/loss in middle-aged and/or older …

Glaucoma is characterized by a continuous loss of retinal ganglion cells. The cause of
glaucoma is associated with an increase in intraocular pressure (IOP), but the underlying …

Acetylcholinesterase (AChE) is responsible for hydrolyzing the acetylcholine
neurotransmitter, bringing an end point to cholinergic neurotransmission. Thus, AChE is the …

Simple Summary Visual loss and blindness caused by retinal disease has a significant
negative effect on the quality of life of many adults and children, and as a result has become …

The applicability of mass spectrometry imaging (MSI) has exponentially increased with the
improvement of sample preparation, instrumentation (spatial resolution) and data analysis …

Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research
allowing analyzes from small samples and low concentrations. This review begins with a …

Fatty acids, and especially docosahexaenoic acid (DHA), are essential for photoreceptor cell
integrity and are involved in the phototransduction cascade. In this study, we analyzed the …

Multiple evidences suggest that mitochondrial dysfunction is implicated in the pathogenesis
of Parkinson's disease via the selective cell death of dopaminergic neurons, such as that …

The retina is an oxidative stress-prone tissue due to high content of polyunsaturated lipids,
exposure to visible light stimuli in the 400–480 nm range, and high oxygen availability …