A systematic review and critical assessment of breast cancer risk prediction tools incorporating a polygenic risk score for the general population
C Mbuya-Bienge, N Pashayan, CD Kazemali… - Cancers, 2023 - mdpi.com
Simple Summary Several risk prediction tools have been developed to better stratify women
according to their risk of developing breast cancer (BC) and inform prevention and early …
according to their risk of developing breast cancer (BC) and inform prevention and early …
Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction
We performed genome-wide association studies of breast cancer including 18,034 cases
and 22,104 controls of African ancestry. Genetic variants at 12 loci were associated with …
and 22,104 controls of African ancestry. Genetic variants at 12 loci were associated with …
Genome-and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics
By combining data from 160,500 individuals with breast cancer and 226,196 controls of
Asian and European ancestry, we conducted genome-and transcriptome-wide association …
Asian and European ancestry, we conducted genome-and transcriptome-wide association …
[HTML][HTML] Breast cancer risk stratification using genetic and non-genetic risk assessment tools for 246,142 women in the UK Biobank
Purpose The benefit of using individual risk prediction tools to identify high-risk individuals
for breast cancer (BC) screening is uncertain, despite the personalized approach of risk …
for breast cancer (BC) screening is uncertain, despite the personalized approach of risk …
A review of disease risk prediction methods and applications in the omics era
C Sun, X Cheng, J Xu, H Chen, J Tao, Y Dong… - …, 2024 - Wiley Online Library
Risk prediction and disease prevention are the innovative care challenges of the 21st
century. Apart from freeing the individual from the pain of disease, it will lead to low medical …
century. Apart from freeing the individual from the pain of disease, it will lead to low medical …
Genetic and lifestyle factors for breast cancer risk assessment in Southeast China
S Zou, Y Lin, X Yu, M Eriksson, M Lin, F Fu… - Cancer …, 2023 - Wiley Online Library
Background Despite the rising incidence and mortality of breast cancer among women in
China, there are currently few predictive models for breast cancer in the Chinese population …
China, there are currently few predictive models for breast cancer in the Chinese population …
Effect of an educational intervention on women's health care provider knowledge gaps about breast cancer risk model use and high-risk screening recommendations
RL Seitzman, JA Pushkin, WA Berg - Journal of Breast Imaging, 2023 - academic.oup.com
Objective To assess effectiveness of a web-based educational intervention on women's
health care provider knowledge of breast cancer risk models and high-risk screening …
health care provider knowledge of breast cancer risk models and high-risk screening …
Utilizing polygenic risk score for breast cancer risk prediction in a Taiwanese population
YH Lin, CC Hung, GC Lin, IC Tsai, CY Lum… - Cancer Epidemiology, 2025 - Elsevier
Background Breast cancer has been the most frequently diagnosed cancer among women
in Taiwan since 2003. While genetic variants play a significant role in the elevated risk of …
in Taiwan since 2003. While genetic variants play a significant role in the elevated risk of …
Polygenic Risk Scores for Breast Cancer
K Demarest, PD Shah - Current Breast Cancer Reports, 2024 - Springer
Abstract Purpose of Review Polygenic risk scores (PRS) for breast cancer (BC) estimate risk
based on the cumulative impact of single-nucleotide polymorphisms. This review outlines …
based on the cumulative impact of single-nucleotide polymorphisms. This review outlines …
Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification
Background Family history, and genetic and non-genetic risk factors can stratify women
according to their individual risk of developing breast cancer. The extent of overlap between …
according to their individual risk of developing breast cancer. The extent of overlap between …