Universal scaling laws rule explosive growth in human cancers

VM Pérez-García, GF Calvo, JJ Bosque… - Nature physics, 2020 - nature.com
Most physical and other natural systems are complex entities that are composed of a large
number of interacting individual elements. It is a surprising fact that they often obey the so …

Tumor Doubling Time and Screening Interval

AA Bhatt, B Niell - Radiologic Clinics, 2024 - radiologic.theclinics.com
The American Cancer Society (ACS) predicts that there will be a greater than 297,000 cases
of invasive ductal carcinoma and 55,000 cases of ductal carcinoma in situ diagnosed in …

[HTML][HTML] Modeling free tumor growth: Discrete, continuum, and hybrid approaches to interpreting cancer development

D Singh, D Paquin - Mathematical Biosciences and Engineering, 2024 - aimspress.com
Tumor growth dynamics serve as a critical aspect of understanding cancer progression and
treatment response to mitigate one of the most pressing challenges in healthcare. The in …

Predicting the effectiveness of chemotherapy using stochastic ODE models of tumor growth

S Sharpe, HM Dobrovolny - Communications in Nonlinear Science and …, 2021 - Elsevier
Ordinary differential equation (ODE) models of cancer growth are often used to predict tumor
growth and form the basis for more complex models used in personalized medicine …

Radiographic and hormonal regression in prolactinomas: An analysis of treatment failure

OO Akinduro, VM Lu, A Izzo, G De Biase, G Vilanilam… - World neurosurgery, 2019 - Elsevier
Objective First-line treatment for prolactin-producing pituitary adenomas is dopamine
agonist (DA) therapy. This is the first study to analyze the rate of radiographic and hormonal …

Function Class Learning with Genetic Programming: Towards Explainable Meta Learning for Tumor Growth Functionals

E Sijben, J Jansen, P Bosman… - Proceedings of the Genetic …, 2024 - dl.acm.org
Paragangliomas are rare, primarily slow-growing tumors for which the underlying growth
pattern is unknown. Therefore, determining the best care for a patient is hard. Currently, if no …

Deep learning-based auto-segmentation of paraganglioma for growth monitoring

EMC Sijben, JC Jansen, M de Ridder… - Medical Imaging …, 2024 - spiedigitallibrary.org
Volume measurement of a paraganglioma (a rare neuroendocrine tumor that typically forms
along major blood vessels and nerve pathways in the head and neck region) is crucial for …

Understanding the effect of measurement time on drug characterization

H Murphy, G McCarthy, HM Dobrovolny - Plos one, 2020 - journals.plos.org
In order to determine correct dosage of chemotherapy drugs, the effect of the drug must be
properly quantified. There are two important values that characterize the effect of the drug: ε …

Investigation of a mathematical model describing global cancer growth and treatment: An inhomogeneous model based on the generalized logistic equation

H Wang, Y Mao, Z Zhang, Z Xu, S Luo, W Li, S Zou… - bioRxiv, 2022 - biorxiv.org
Tumor growth is manifestation of the evolution of a complex system. Researchers have
limited scope of modelling studies on specific aspects or stages of the process. It has led to …

Mathematical Modeling of Cellular Exhaustion to Guide Future Immunotherapy Research

TN Simmons - 2024 - search.proquest.com
Cellular exhaustion is a dysfunction found in various adaptive immune cells. In chronic
settings, like cancer, antigen persistence and prolonged stimulation initiates the …