Filamentous fungi are highly productive cell factories, many of which are industrial
producers of enzymes, organic acids, and secondary metabolites. The increasing number of …

Fungi represent an important source of bioactive secondary metabolites (SMs), which have
wide applications in many fields, including medicine, agriculture, human health, and many …

ABSTRACT CRISPR/Cas9 genome editing technology has been implemented in almost all
living organisms. Its editing precision appears to be very high and therefore could represent …

Covering: up to May 2022 Fungal genetics has transformed natural product research by
enabling the elucidation of cryptic metabolites and biosynthetic steps. The enhanced …

Filamentous fungi are an important source of natural products. The mold Penicillium
roqueforti, which is well-known for being responsible for the characteristic texture, blue …

Penicillium roqueforti is used worldwide in the production of blue-veined cheese. The blue-
green colour derives from pigmented spores formed by fungal growth. Using a combination …

Melanin is a heteropolymer formed by the polymerization of phenolic and indolic
compounds. It occurs in organisms across all biological kingdoms and has a range different …

Penicillium digitatum and Penicillium expansum are plant pathogenic fungi that cause the
green and blue mold diseases, respectively, leading to serious postharvest economic losses …

Venturia inaequalis is the ascomycetous pathogen causing apple scabs and forms dark-
pigmented spores and partially melanised infection structures. Although melanin is …

The regulation of fungal specialized metabolism is a complex process involving various
regulators. Among these regulators, LaeA, a methyltransferase protein originally discovered …