The mechanistic (or mammalian) target of rapamycin (mTOR) is considered as a critical
regulatory enzyme involved in essential signaling pathways affecting cell growth, cell …

Renal interstitial fibrosis is the pathological basis of end-stage renal disease, in which the
heterogeneity of macrophages in renal microenvironment plays an important role. However …

The protozoan parasite Leishmania donovani (L. donovani) causes visceral leishmaniasis, a
chronic infection which is fatal when untreated. Herein, we investigated whether in addition …

HuR is a miRNA derepressor protein that can act as miRNA sponge for specific miRNAs to
negate their action on target mRNAs. Here we have identified how HuR, by inducing …

Leishmania donovani infection of macrophages drives profound changes in the metabolism
of both the host macrophage and the parasite, which undergoes different phases of …

Congenital toxoplasmosis can cause neurological and eye damage, behavioral alterations,
or death in fetuses or babies born to Toxoplasma gondii-infected women. Several pieces of …

Chemokine CXC motif ligand 16 (CXCL16) is an important mediator that has been shown to
participate in various human diseases. The role of CXCL16 in the immunopathology of …

Objective: This study was aimed at investigating the immunoregulatory effects of
trypanosomal lipophosphoglycan (LPG) anchored to trypanosome membranes, including …

Objective: The health consequences among COVID-19 convalescent patients 30 months
post-infection were described and the potential risk factors were determined. Methods: In …

Introdução: A Leishmania é um parasito intracelular capaz de causar lesão na pele, mucosa
e órgãos internos. A disseminação e homing de células infectadas contendo antígenos do …