Heavy metal transporters: Functional mechanisms, regulation, and application in phytoremediation

Z Yang, F Yang, JL Liu, HT Wu, H Yang, Y Shi… - Science of the Total …, 2022 - Elsevier
Heavy metal pollution in soil is a global problem with serious impacts on human health and
ecological security. Phytoextraction in phytoremediation, in which plants uptake and …

[HTML][HTML] Flipping the switch: dynamic modulation of membrane transporter activity in bacteria

R Elston, C Mulligan, GH Thomas - Microbiology, 2023 - microbiologyresearch.org
The controlled entry and expulsion of small molecules across the bacterial cytoplasmic
membrane is essential for efficient cell growth and cellular homeostasis. While much is …

Structural and functional characterizations of the C-terminal domains of CzcD proteins

SR Udagedara, DM La Porta, C Spehar… - Journal of Inorganic …, 2020 - Elsevier
Zinc is a potent antimicrobial component of the innate immune response at the host-
pathogen interface. Bacteria subvert or resist host zinc insults by metal efflux pathways that …

[HTML][HTML] Metal transport mechanism of the cation diffusion facilitator (CDF) protein family–a structural perspective on human CDF (ZnT)-related diseases

S Barber-Zucker, A Moran, R Zarivach - RSC chemical biology, 2021 - pubs.rsc.org
Divalent d-block metal cations (DDMCs) participate in many cellular functions; however,
their accumulation in cells can be cytotoxic. The cation diffusion facilitator (CDF) family is a …

Paramagnetic species in catalysis research: a unified approach towards (the role of EPR in) heterogeneous, homogeneous and enzyme catalysis

M Bracci, PC Bruzzese, A Famulari, D Fioco, A Guidetti… - 2020 - books.rsc.org
Paramagnetic (open-shell) systems, including transition metal ions, radical intermediates
and defect centres, are often involved in catalytic transformations. Despite the prevalence of …

[HTML][HTML] Molecular Basis of Energy Crops Functioning in Bioremediation of Heavy Metal Pollution

S Huang, Z Lu, X Zhao, W Tan, H Wang, D Liu, W Xing - Agriculture, 2024 - mdpi.com
Heavy metal pollution is a gradually growing environmental issue that hinders the growth
and development of plants, and also destabilizes soil. Consequently, eco-friendly …

[HTML][HTML] The cation diffusion facilitator protein MamM's cytoplasmic domain exhibits metal-type dependent binding modes and discriminates against Mn2+

S Barber-Zucker, J Hall, A Froes, S Kolusheva… - Journal of Biological …, 2020 - ASBMB
Cation diffusion facilitator (CDF) proteins are a conserved family of divalent transition metal
cation transporters. CDF proteins are usually composed of two domains: the transmembrane …

Advanced EPR spectroscopy for investigation of biomolecular binding events

JL Wort, M Oranges, K Ackermann, BE Bode - 2020 - books.rsc.org
The emergence of systems biology in the post-genomic era has led to investigating
increasingly complex macromolecular assemblies, emphasising holistic approaches in …

[HTML][HTML] The metal binding site composition of the cation diffusion facilitator protein MamM cytoplasmic domain impacts its metal responsivity

S Barber-Zucker, A Shahar, S Kolusheva, R Zarivach - Scientific reports, 2020 - nature.com
The cation diffusion facilitator (CDF) is a conserved family of divalent d-block metal cation
transporters that extrude these cations selectively from the cytoplasm. CDF proteins are …

To bind or not to bind-dissociation equilibria studied by pulse dipolar EPR

J Wort - 2022 - research-repository.st-andrews.ac …
Pulse dipolar EPR is an appealing strategy for structural characterisation of complex
systems in solution that complements other biophysical techniques. Significantly, the …