Roles of oxidative stress in polycystic ovary syndrome and cancers

T Zuo, M Zhu, W Xu - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Oxidative stress (OS) has received extensive attention in the last two decades, because of
the discovery that abnormal oxidation status was related to patients with chronic diseases …

Insulin and the polycystic ovary syndrome

D Macut, J Bjekić-Macut, D Rahelić, M Doknić - Diabetes research and …, 2017 - Elsevier
Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy among women
during reproductive age. PCOS is characterised by hyperandrogenaemia …

Nonalcoholic fatty liver disease in women with polycystic ovary syndrome

SA Paschou, SA Polyzos, P Anagnostis, DG Goulis… - Endocrine, 2020 - Springer
Polycystic ovary syndrome (PCOS) affects 6–15% of women of reproductive age.
Nonalcoholic fatty liver disease (NAFLD) affects 25–30% of the general population and its …

Glucocorticoid sexual dimorphism in metabolism: dissecting the role of sex hormones

J Kroon, AM Pereira, OC Meijer - Trends in Endocrinology & Metabolism, 2020 - cell.com
Glucocorticoids are steroid hormones that are of pivotal importance in human physiology.
Glucocorticoid signaling is complex in nature and dependent on many interacting factors. As …

Management of endocrine disease: Polycystic ovary syndrome and nonalcoholic fatty liver disease

D Macut, I Božić-Antić, J Bjekić-Macut… - European journal of …, 2017 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a frequent endocrine disease in women, with a
number of metabolic and reproductive consequences. Obesity, insulin resistance (IR) and …

Overfeeding in the early postnatal period aggravates inflammation and hepatic insulin sensitivity in the 5α-dihydrotestosterone-induced animal model of PCOS

N Veličković, B Mićić, A Teofilović… - Frontiers in …, 2024 - frontiersin.org
Background Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in
women of reproductive age and is closely associated with chronic low-grade inflammation …

Combined androgen excess and Western-style diet accelerates adipose tissue dysfunction in young adult, female nonhuman primates

O Varlamov, CV Bishop, M Handu… - Human …, 2017 - academic.oup.com
STUDY QUESTION What are the separate and combined effects of mild
hyperandrogenemia and consumption of a high-fat Western-style diet (WSD) on white …

AMPK Activation as a Protective Mechanism to Restrain Oxidative Stress in the Insulin-Resistant State in Skeletal Muscle of Rat Model of PCOS Subjected to Postnatal …

B Mićić, A Djordjevic, N Veličković, S Kovačević… - Biomedicines, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is a common endocrinopathy in women of reproductive
age, often associated with obesity and insulin resistance. Childhood obesity is an important …

Synergistic effects of hyperandrogenemia and obesogenic western-style diet on transcription and DNA methylation in visceral adipose tissue of nonhuman primates

L Carbone, BA Davis, SS Fei, A White, KA Nevonen… - Scientific reports, 2019 - nature.com
Polycystic ovary syndrome (PCOS) is a major reproductive disorder that is responsible for
80% of anovulatory infertility and that is associated with hyperandrogenemia, increased risk …

Nonalcoholic fatty liver disease in patients with polycystic ovary syndrome

D Macut, J Bjekić-Macut, S Livadas… - Current …, 2018 - ingentaconnect.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women during
the reproductive period. True PCOS phenotype is prone to develop metabolic …