Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment

Y Dai, C Xu, X Sun, X Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …

Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies

K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

Enzyme responsive drug delivery systems in cancer treatment

M Shahriari, M Zahiri, K Abnous, SM Taghdisi… - Journal of Controlled …, 2019 - Elsevier
Recent technological approaches in drug delivery have attracted scientist interest for
improving therapeutic index of medicines and drug compliance. One of the powerful …

[HTML][HTML] Recent advances in multifunctional nanomaterials for photothermal-enhanced Fenton-based chemodynamic tumor therapy

P Manivasagan, A Joe, HW Han, T Thambi… - Materials Today Bio, 2022 - Elsevier
Abstract Photothermal (PT)-enhanced Fenton-based chemodynamic therapy (CDT) has
attracted a significant amount of research attention over the last five years as a highly …

Iron oxide based nanoparticles for multimodal imaging and magnetoresponsive therapy

N Lee, D Yoo, D Ling, MH Cho, T Hyeon… - Chemical …, 2015 - ACS Publications
Magnetic nanoparticles have received tremendous attention in diverse fields because of
their unique nanoscale physicochemical properties and the potential for a wide range of …

[HTML][HTML] Iron oxide nanoparticles and their pharmaceutical applications

NF Attia, EM Abd El-Monaem, HG El-Aqapa… - Applied Surface Science …, 2022 - Elsevier
The importance of different polymorphic forms of iron oxide nanoparticles attracted a lot of
attentions in various applications due to their unique electrical, optical and magnetic …

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

S Zanganeh, G Hutter, R Spitler, O Lenkov… - Nature …, 2016 - nature.com
Until now, the Food and Drug Administration (FDA)-approved iron supplement ferumoxytol
and other iron oxide nanoparticles have been used for treating iron deficiency, as contrast …

The rebirth of matrix metalloproteinase inhibitors: moving beyond the dogma

GB Fields - Cells, 2019 - mdpi.com
The pursuit of matrix metalloproteinase (MMP) inhibitors began in earnest over three
decades ago. Initial clinical trials were disappointing, resulting in a negative view of MMPs …

Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt (IV) pro-drug

MA Miller, YR Zheng, S Gadde, C Pfirschke… - Nature …, 2015 - nature.com
Therapeutic nanoparticles (TNPs) aim to deliver drugs more safely and effectively to
cancers, yet clinical results have been unpredictable owing to limited in vivo understanding …

[HTML][HTML] Recent advances in nanocarrier-assisted therapeutics delivery systems

S Su, PM Kang - Pharmaceutics, 2020 - mdpi.com
Nanotechnologies have attracted increasing attention in their application in medicine,
especially in the development of new drug delivery systems. With the help of nano-sized …