AI in health and medicine

P Rajpurkar, E Chen, O Banerjee, EJ Topol - Nature medicine, 2022 - nature.com
Artificial intelligence (AI) is poised to broadly reshape medicine, potentially improving the
experiences of both clinicians and patients. We discuss key findings from a 2-year weekly …

Superresolution structured illumination microscopy reconstruction algorithms: a review

X Chen, S Zhong, Y Hou, R Cao, W Wang… - Light: Science & …, 2023 - nature.com
Structured illumination microscopy (SIM) has become the standard for next-generation wide-
field microscopy, offering ultrahigh imaging speed, superresolution, a large field-of-view …

Democratising deep learning for microscopy with ZeroCostDL4Mic

L von Chamier, RF Laine, J Jukkala, C Spahn… - Nature …, 2021 - nature.com
Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and …

Evaluation and development of deep neural networks for image super-resolution in optical microscopy

C Qiao, D Li, Y Guo, C Liu, T Jiang, Q Dai, D Li - Nature methods, 2021 - nature.com
Deep neural networks have enabled astonishing transformations from low-resolution (LR) to
super-resolved images. However, whether, and under what imaging conditions, such deep …

Small-molecule fluorogenic probes for mitochondrial nanoscale imaging

R Zhai, B Fang, Y Lai, B Peng, H Bai, X Liu… - Chemical Society …, 2023 - pubs.rsc.org
Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …

A survey on applications of deep learning in microscopy image analysis

Z Liu, L Jin, J Chen, Q Fang, S Ablameyko, Z Yin… - Computers in biology …, 2021 - Elsevier
Advanced microscopy enables us to acquire quantities of time-lapse images to visualize the
dynamic characteristics of tissues, cells or molecules. Microscopy images typically vary in …

[HTML][HTML] Live-cell imaging in the deep learning era

JW Pylvänäinen, E Gómez-de-Mariscal… - Current Opinion in Cell …, 2023 - Elsevier
Live imaging is a powerful tool, enabling scientists to observe living organisms in real time.
In particular, when combined with fluorescence microscopy, live imaging allows the …

Three-dimensional residual channel attention networks denoise and sharpen fluorescence microscopy image volumes

J Chen, H Sasaki, H Lai, Y Su, J Liu, Y Wu… - Nature …, 2021 - nature.com
We demonstrate residual channel attention networks (RCAN) for the restoration and
enhancement of volumetric time-lapse (four-dimensional) fluorescence microscopy data …

Three-dimensional structured illumination microscopy with enhanced axial resolution

X Li, Y Wu, Y Su, I Rey-Suarez, C Matthaeus… - Nature …, 2023 - nature.com
The axial resolution of three-dimensional structured illumination microscopy (3D SIM) is
limited to∼ 300 nm. Here we present two distinct, complementary methods to improve axial …

Resolution doubling in light-sheet microscopy via oblique plane structured illumination

B Chen, BJ Chang, P Roudot, F Zhou, E Sapoznik… - Nature …, 2022 - nature.com
Structured illumination microscopy (SIM) doubles the spatial resolution of a fluorescence
microscope without requiring high laser powers or specialized fluorophores. However, the …