Basal forebrain cholinergic system and orexin neurons: effects on attention
I Villano, A Messina, A Valenzano… - Frontiers in behavioral …, 2017 - frontiersin.org
The basal forebrain (BF) cholinergic system has an important role in attentive functions. The
cholinergic system can be activated by different inputs, and in particular, by orexin neurons …
cholinergic system can be activated by different inputs, and in particular, by orexin neurons …
Physiologically-based modeling of sleep–wake regulatory networks
Mathematical modeling has played a significant role in building our understanding of sleep–
wake and circadian behavior. Over the past 40 years, phenomenological models, including …
wake and circadian behavior. Over the past 40 years, phenomenological models, including …
Are individual differences in sleep and circadian timing amplified by use of artificial light sources?
K Swaminathan, EB Klerman… - Journal of biological …, 2017 - journals.sagepub.com
Within the human population, there is large interindividual variability in the timing of sleep
and circadian rhythms. This variability has been attributed to individual differences in sleep …
and circadian rhythms. This variability has been attributed to individual differences in sleep …
[HTML][HTML] Circuit mechanisms and computational models of REM sleep
Rapid eye movement (REM) sleep or paradoxical sleep is an elusive behavioral state. Since
its discovery in the 1950s, our knowledge of the neuroanatomy, neurotransmitters and …
its discovery in the 1950s, our knowledge of the neuroanatomy, neurotransmitters and …
REM sleep loss–induced elevated noradrenaline could predispose an individual to psychosomatic disorders: a review focused on proposal for prediction, prevention …
Historically and traditionally, it is known that sleep helps in maintaining healthy living. Its
duration varies not only among individuals but also in the same individual depending on …
duration varies not only among individuals but also in the same individual depending on …
Evaluating the evidence surrounding pontine cholinergic involvement in REM sleep generation
Rapid eye movement (REM) sleep–characterized by vivid dreaming, motor paralysis, and
heightened neural activity–is one of the fundamental states of the mammalian central …
heightened neural activity–is one of the fundamental states of the mammalian central …
A thalamocortical neural mass model of the EEG during NREM sleep and its response to auditory stimulation
M Schellenberger Costa, A Weigenand… - PLoS computational …, 2016 - journals.plos.org
Few models exist that accurately reproduce the complex rhythms of the thalamocortical
system that are apparent in measured scalp EEG and at the same time, are suitable for large …
system that are apparent in measured scalp EEG and at the same time, are suitable for large …
A physiologically based model of orexinergic stabilization of sleep and wake
The orexinergic neurons of the lateral hypothalamus (Orx) are essential for regulating sleep-
wake dynamics, and their loss causes narcolepsy, a disorder characterized by severe …
wake dynamics, and their loss causes narcolepsy, a disorder characterized by severe …
REM sleep loss associated changes in orexin-A levels in discrete brain areas in rats
Rapid eye movement sleep (REMS) serves house-keeping function of the brain and its loss
affects several pathophysiological processes. Relative levels of neurotransmitters including …
affects several pathophysiological processes. Relative levels of neurotransmitters including …
Mammalian rest/activity patterns explained by physiologically based modeling
AJK Phillips, BD Fulcher, PA Robinson… - PLoS Computational …, 2013 - journals.plos.org
Circadian rhythms are fundamental to life. In mammals, these rhythms are generated by
pacemaker neurons in the suprachiasmatic nucleus (SCN) of the hypothalamus. The SCN is …
pacemaker neurons in the suprachiasmatic nucleus (SCN) of the hypothalamus. The SCN is …