VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy

A Arrigo, E Aragona, F Bandello - Annals of medicine, 2022 - Taylor & Francis
Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes
mellitus, representing a major cause of visual impairment in developed countries …

Anti‐vascular endothelial growth factor for diabetic macular oedema

G Virgili, M Parravano, F Menchini… - Cochrane Database of …, 2014 - cochranelibrary.com
Background Diabetic macular oedema (DMO) is a common complication of diabetic
retinopathy. Although grid or focal laser photocoagulation has been shown to reduce the risk …

Efficacy and safety of intravitreal anti-VEGF therapy in diabetic retinopathy: what we have learned and what should we learn further?

G Uludag, M Hassan, W Matsumiya… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Diabetic retinopathy (DR) is one of the most frequent microvascular
complications of diabetes that can lead to blindness. Laser treatment has been the gold …

Intravitreal therapy for diabetic macular edema: an update

C Furino, F Boscia, M Reibaldi… - Journal of …, 2021 - Wiley Online Library
Diabetic macular edema (DME) represents a prevalent and disabling eye condition. Despite
that DME represents a sight‐threatening condition, it is also among the most accessible to …

Diabetic retinopathy in China: Epidemiology, screening and treatment trends—A review

X Li, TE Tan, TY Wong, X Sun - Clinical & Experimental …, 2023 - Wiley Online Library
Diabetic retinopathy (DR) is the leading cause of vision impairment in the global working‐
age population. In China, with one‐third of the world's diabetes population estimated at 141 …

Cardiovascular adverse events with intravitreal anti–vascular endothelial growth factor drugs: a systematic review and meta-analysis of randomized clinical trials

NN Ntjam, M Thulliez, G Paintaud, F Salvo… - JAMA …, 2021 - jamanetwork.com
Importance Systemic safety of intravitreal anti-vascular endothelial growth factor (anti-VEGF)
is a matter of debate and regular updates are necessary. Objective To evaluate systemic …

Comparative efficacy, durability and safety of faricimab in the treatment of diabetic macular edema: a systematic literature review and network meta-analysis

C Watkins, T Paulo, C Buehrer, NM Holekamp… - Advances in …, 2023 - Springer
Introduction A systematic literature review (SLR) and network meta-analysis (NMA) were
conducted to evaluate the comparative efficacy, durability and safety of faricimab, used in a …

Treatment of macular edema in vascular retinal diseases: a 2021 update

A Grzybowski, A Markeviciute, R Zemaitiene - Journal of clinical medicine, 2021 - mdpi.com
Macular edema (ME) is associated with various conditions; however, the main causes of ME
are retinal vein occlusion (RVO) and diabetes. Laser photocoagulation, formerly the gold …

Efficacy, Durability, and Safety of Faricimab in Patients From Asian Countries With Diabetic Macular Edema: 1-Year Subgroup Analysis of the Phase III YOSEMITE and …

S Ishida, SJ Chen, T Murata, Y Ogura… - The Asia-Pacific …, 2023 - journals.lww.com
Purpose: To assess the 1-year efficacy, durability, and safety of faricimab in patients with
diabetic macular edema from Asian and non-Asian countries. Design: Global, multicenter …

Managing diabetic macular edema in clinical practice: systematic review and meta-analysis of current strategies and treatment options

D Veritti, V Sarao, V Soppelsa… - Clinical Ophthalmology, 2021 - Taylor & Francis
Purpose This meta-analysis aims to summarize 12-month best-corrected visual acuity
(BCVA) outcomes in response to anti-vascular endothelial growth factor (VEGF) therapy and …