Myasthenia gravis (MG) is an autoimmune disease caused by antibodies which attack receptors at the neuromuscular junction. One of the main difficulties in predicting the clinical …
T Punga, R Le Panse, M Andersson… - Annals of clinical …, 2014 - Wiley Online Library
Objective Myasthenia gravis (MG) is a chronic autoimmune disorder where autoantibodies target the nicotinic acetylcholine receptors (AChR+) in about 85% of cases, in which the …
AR Punga, T Punga - Annals of the New York Academy of …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are small noncoding RNA molecules that bind to specific mRNA targets and regulate a wide range of important biological processes within cells. Circulating …
Human adenoviruses (HAdVs) are common pathogens causing a variety of respiratory, ocular and gastrointestinal diseases. To accomplish their efficient replication, HAdVs take an …
Virus infected immune cells can rapidly respond to the invader by activating the inflammasome and as a consequence release proinflammatory cytokines and eventually die …
O Ruuskanen, JP Metcalf, O Meurman… - Clinical …, 2009 - Wiley Online Library
The human adenoviruses comprise 51 distinct serotypes that are grouped into six subgroups (A to F) based on various immunologic, biological, and biochemical …
D Piedade, JM Azevedo-Pereira - Frontiers in Microbiology, 2017 - frontiersin.org
MicroRNAs (miRNAs) are powerful regulators of gene expression and fine-tuning genes in all tissues. Cellular miRNAs can control 100s of biologic processes (eg, morphogenesis of …
W Kamel, B Segerman, T Punga, G Akusjärvi - PLoS One, 2014 - journals.plos.org
Human adenoviruses (HAds) encode for one or two highly abundant virus-associated RNAs, designated VA RNAI and VA RNAII, which fold into stable hairpin structures resembling …
Human adenoviruses (HAdVs) are common pathogens associated with a wide variety of respiratory, ocular, and gastrointestinal diseases. To achieve its effective lytic mode of …