Parkinson's disease (PD) is a significantly progressive neurodegenerative disease
characterised by both motor and nonmotor disorders. The main pathological characteristics …

Epidemiological studies indicate that physical activity and exercise may reduce the risk of
developing Parkinson's disease (PD), and clinical observations suggest that physical …

The hippocampus is particularly susceptible to neurodegeneration. Physical activity,
specifically increasing cardiorespiratory fitness via aerobic exercise, shows promise as a …

Aim. This study was aimed at investigating the effects and molecular mechanisms of
physical activity intervention on Parkinson's disease (PD) and providing theoretical …

Background Parkinson's disease (PD) is one of the most common neurodegenerative
diseases in the elderly. Cognitive dysfunction represents a common and challenging non …

A paradox is a seemingly absurd or impossible concept, proposition, or theory that is often
difficult to understand or explain, sometimes apparently self-contradictory, and yet ultimately …

Behavioral impulsivity is common in various psychiatric and metabolic disorders. Here we
identify a hypothalamus to telencephalon neural pathway for regulating impulsivity involving …

Disease-modifying treatments remain an unmet medical need in Parkinson's disease (PD).
Such treatments can be operationally defined as interventions that slow down the clinical …

Background Aerobic exercise training (AET) has been shown to provide general health
benefits, and to improve motor behaviours in particular, in individuals with Parkinson's …

Prepulse inhibition (PPI) is a neuropsychological process during which a weak sensory
stimulus (“prepulse”) attenuates the motor response (“startle reaction”) to a subsequent …