RJ Woods - Chemical reviews, 2018 - ACS Publications
Complex carbohydrates are ubiquitous in nature, and together with proteins and nucleic acids they comprise the building blocks of life. But unlike proteins and nucleic acids …
H Heine, A Zamyatina - Pharmaceuticals, 2022 - mdpi.com
The Toll-like receptor 4 (TLR4) signaling pathway plays a central role in the prompt defense against infectious challenge and provides immediate response to Gram-negative bacterial …
R Baron, JA McCammon - Annual review of physical chemistry, 2013 - annualreviews.org
We review recent developments in our understanding of molecular recognition and ligand association, focusing on two major viewpoints:(a) studies that highlight new physical insight …
This article presents a reoptimization of the GROMOS 53A6 force field for hexopyranose‐ based carbohydrates (nearly equivalent to 45A4 for pure carbohydrate systems) into a new …
Infection and viral entry of SARS-CoV-2 crucially depends on the binding of its Spike protein to angiotensin converting enzyme 2 (ACE2) presented on host cells. Glycosylation of both …
E Fadda - Current Opinion in Chemical Biology, 2022 - Elsevier
Complex carbohydrates (glycans) are the most abundant and versatile biopolymers in nature. The broad diversity of biochemical functions that carbohydrates cover is a direct …
Cello-oligosaccharides (COS) are small carbohydrate molecules derived from cellulose through partial hydrolysis. COS exert physiological influence on plants, animals and humans …
Although there have been substantial improvements in glycan analysis over the past decade, the lack of both high-resolution and high-throughput methods hampers progress in …