D Gumber, LD Wang - EBioMedicine, 2022 - thelancet.com
Chimeric antigen receptor (CAR) T cell therapy has emerged as a cancer treatment with enormous potential, demonstrating impressive antitumor activity in the treatment of …
P Glynne, N Tahmasebi, V Gant… - Journal of Investigative …, 2022 - journals.sagepub.com
Long COVID is characterized by the emergence of multiple debilitating symptoms following SARS-CoV-2 infection. Its etiology is unclear and it often follows a mild acute illness …
S Nkongolo, D Mahamed, A Kuipery… - The Journal of …, 2023 - Am Soc Clin Investig
Accumulation of activated immune cells results in nonspecific hepatocyte killing in chronic hepatitis B (CHB), leading to fibrosis and cirrhosis. This study aims to understand the …
JK Files, S Boppana, MD Perez… - The Journal of …, 2021 - Am Soc Clin Investig
Ongoing observational clinical research has prioritized understanding the human immune response to SARS-CoV-2 during the coronavirus disease 2019 (COVID-19) pandemic …
RY Chen, Y Zhu, YY Shen, QY Xu, HY Tang… - Frontiers in …, 2023 - frontiersin.org
Programmed cell death 1 receptor (PD-1) and its ligands constitute an inhibitory pathway to mediate the mechanism of immune tolerance and provide immune homeostasis …
J Westmeier, K Paniskaki, Z Karaköse, T Werner… - MBio, 2020 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces a T cell response that most likely contributes to virus control in COVID-19 patients but may also …
M Khan, Z Zhao, S Arooj, Y Fu, G Liao - Frontiers in immunology, 2020 - frontiersin.org
Programmed death protein 1 (PD-1) interaction with PD-L1 deliver immunosuppressive environment for tumor growth, and its blockade with directed monoclonal antibodies (anti …
SARS-CoV-2 is responsible for an ongoing pandemic that has affected millions of individuals around the globe. To gain further understanding of the immune response in …
Z Guo, Z Zhang, M Prajapati, Y Li - Viruses, 2021 - mdpi.com
Viral infections can give rise to a systemic decrease in the total number of lymphocytes in the blood, referred to as lymphopenia. Lymphopenia may affect the host adaptive immune …