Mechanical properties of female reproductive organs and supporting connective tissues: a review of the current state of knowledge

A Baah-Dwomoh, J McGuire… - Applied …, 2016 - asmedigitalcollection.asme.org
Although there has been an upsurge of interest in research on women's sexual and
reproductive health, most of the research has remained confined to the obstetrics and …

Animal models for pelvic organ prolapse: systematic review

MGMC Mori da Cunha, K Mackova… - International …, 2021 - Springer
Introduction and hypothesis We aimed to summarize the knowledge on the pathogenesis of
pelvic organ prolapse (POP) generated in animal models. Methods We searched MEDLINE …

Cervical softening occurs early in pregnancy: characterization of cervical stiffness in 100 healthy women using the aspiration technique

S Badir, E Mazza, R Zimmermann… - Prenatal diagnosis, 2013 - Wiley Online Library
Objective To quantitatively describe the evolution of ectocervical stiffness in normal
pregnancy. Methods The stiffness of ectocervical tissue was measured by using the …

Pregnancy-induced remodeling of the murine reproductive tract: a longitudinal in vivo magnetic resonance imaging study

AC Suarez, CJ Gimenez, SR Russell, M Wang… - Scientific Reports, 2024 - nature.com
Mammalian pregnancy requires gradual yet extreme remodeling of the reproductive organs
to support the growth of the embryos and their birth. After delivery, the reproductive organs …

Smooth muscle regional contribution to vaginal wall function

GL Clark, AP Pokutta-Paskaleva… - Interface …, 2019 - royalsocietypublishing.org
Pelvic organ prolapse is characterized as the descent of the pelvic organs into the vaginal
canal. In the USA, there is a 12% lifetime risk for requiring surgical intervention. Although …

Pregnancy-induced adaptations in intramuscular extracellular matrix of rat pelvic floor muscles

M Alperin, T Kaddis, R Pichika, MC Esparza… - American journal of …, 2016 - Elsevier
Background Birth trauma to pelvic floor muscles is a major risk factor for pelvic floor
disorders. Intramuscular extracellular matrix determines muscle stiffness, supports …

Alterations in the structural characteristics of rectus abdominis muscles caused by diabetes and pregnancy: A comparative study of the rat model and women

G Vesentini, AMP Barbosa, DC Damasceno, G Marini… - PLoS …, 2020 - journals.plos.org
Background and objective In the present study, we compared the effect of diabetic
pregnancy on the rectus abdominis muscle (RAM) in humans and rats. We hypothesized …

Strains induced in the vagina by smooth muscle contractions

A Huntington, SD Abramowitch, PA Moalli, R De Vita - Acta biomaterialia, 2021 - Elsevier
The ability of the vagina to contract gives rise to a set of active mechanical properties that
contribute to the complex function of this organ in-vivo. Regional differences in the …

Anisotropy of the passive and active rat vagina under biaxial loading

A Huntington, E Rizzuto, S Abramowitch… - Annals of Biomedical …, 2019 - Springer
Pelvic organ prolapse, the descent of the pelvic organs from their normal anatomical
position, is a common condition among women that is associated with mechanical …

Biomechanical and morphological properties of the multiparous ovine vagina and effect of subsequent pregnancy

R Rynkevic, P Martins, L Hympanova, H Almeida… - Journal of …, 2017 - Elsevier
Pelvic floor soft tissues undergo changes during the pregnancy. However, the degree and
nature of this process is not completely characterized. This study investigates the effect of …