A Comprehensive Review of Andrographis paniculata (Burm. f.) Nees and Its Constituents as Potential Lead Compounds for COVID-19 Drug Discovery

A Intharuksa, W Arunotayanun, W Yooin, P Sirisa-Ard - Molecules, 2022 - mdpi.com
The COVID-19 pandemic has intensively disrupted global health, economics, and well-
being. Andrographis paniculata (Burm. f.) Nees has been used as a complementary …

Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology

A Okhuarobo, JE Falodun, O Erharuyi, V Imieje… - Asian Pacific journal of …, 2014 - Elsevier
Abstract Andrographis paniculata Wall (family Acanthaceae) is one of the most popular
medicinal plants used traditionally for the treatment of array of diseases such as cancer …

Acetaminophen-induced liver injury: Molecular mechanism and treatments from natural products

J Liao, Q Lu, Z Li, J Li, Q Zhao, J Li - Frontiers in pharmacology, 2023 - frontiersin.org
Acetaminophen (APAP) is a widely used analgesic and antipyretic over-the-counter
medicine worldwide. Hepatotoxicity caused by APAP overdose is one of the leading causes …

Anticancer potential of andrographolide from Andrographis paniculata (Burm. f.) Nees and its mechanisms of action

Z Malik, R Parveen, B Parveen, S Zahiruddin… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Synthetic drugs used for cancer treatment have side
effects that may be immunosupressive, can cause liver, kidney and cardiac toxicity, and …

[PDF][PDF] A review on role of plant (s) extracts and its phytochemicals for the management of diabetes

M Govindappa - J Diabetes Metab, 2015 - researchgate.net
The present review focused on plant extracts or phytochemicals role in diabetes
management has been tried by many researchers. I have attempted to compile a list of total …

A bitter plant with a sweet future? A comprehensive review of an oriental medicinal plant: Andrographis paniculata

R Subramanian, M Zaini Asmawi, A Sadikun - Phytochemistry reviews, 2012 - Springer
Abstract Andrographis paniculata (Burm. f) Nees is one of the most popular and important
medicinal plant of the Orient, and South East Asia. It finds mention in various forms in Indian …

Andrographolide nanophytosomes exhibit enhanced cellular delivery and pro-apoptotic activities in HepG2 liver cancer cells

T Neamatallah, AM Malebari, AJ Alamoudi… - Drug Delivery, 2023 - Taylor & Francis
Andrographolide (AG), a major active constituent of Andrographis paniculata, is known to
hinder proliferation of several types of cancer cells. However, its poor solubility and cellular …

[HTML][HTML] Interaction between warfarin and Chinese herbal medicines

YT Chua, XL Ang, XM Zhong… - Singapore medical journal, 2015 - ncbi.nlm.nih.gov
In traditional Chinese medicine (TCM), the human body is divided into Yin and Yang.
Diseases occur when the Yin and Yang balance is disrupted. Different herbs are used to …

Andrographis paniculata transcriptome provides molecular insights into tissue-specific accumulation of medicinal diterpenes

A Garg, L Agrawal, RC Misra, S Sharma, S Ghosh - BMC genomics, 2015 - Springer
Abstract Background Kalmegh (Andrographis paniculata) has been widely exploited in
traditional medicine for the treatment of infectious diseases and health disorders. Ent …

Polypharmacology of andrographolide: Beyond one molecule one target

QTN Tran, WSD Tan, WSF Wong, CLL Chai - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 1951 to 2020 Andrographolide is one of the most widely studied plant secondary
metabolites, known to display diverse pharmacological actions. Current literature has …