T2DM is a complex metabolic disorder characterized by hyperglycemia and glucose
intolerance. It is recognized as one of the most common metabolic disorders and its …

Brain aging is linked to certain types of neurodegenerative diseases and identifying new
therapeutic targets has become critical. Melatonin, a pineal hormone, associates with …

High fat diet-induced obesity is associated with insulin resistance (IR) and other chronic, diet
related illnesses, including dementia. Alzheimer disease is the most common form of …

Global obesity is a pandemic status, estimated to affect over 2 billion people, that has
resulted in an enormous strain on healthcare systems worldwide. The situation is …

Diabetes and Alzheimer's disease are common chronic illnesses in the United States and
lack clearly demonstrated therapeutics. Mitochondria, the “powerhouse of the cell”, is …

High-caloric diet and physical inactivity predispose individuals to obesity and diabetes,
which are risk factors of hippocampal neurodegeneration and cognitive deficits. Along with …

Abstract Epigallocatechin-3-gallate (EGCG), a catechin found in green tea, has been
previously investigated for its neuroprotective effects in vitro and in vivo. In the present study …

Type 2 diabetes mellitus is a complicated metabolic disorder characterized by
hyperglycemia and glucose intolerance. Alzheimer's disease is a progressive brain disorder …

Recent evidence showed that amylin deposition is not only found in the pancreas in type 2
diabetes mellitus (T2DM) patients, but also in other peripheral organs, such as kidneys …

The pancreatic peptide amylin is best known for its role as a satiation hormone in the control
of food intake and as the major component of islet amyloid deposits in the pancreatic islets …