Bio-imaging, by enabling the visualization of biomolecules of interest, has proved to be
highly informative in the study of biological processes. Although fluorescence microscopy is …

Overexpressed neuropeptide receptors allow tumor visualization using eg radiolabeled
peptidic receptor ligands and positron emission tomography (PET) or single photon …

In developed countries, cancer is the second leading cause of death, being only surpassed
by cardiovascular diseases. To develop tumor-targeted tools to localize and treat cancer at …

Studies concerning the development of radiopharmaceuticals based on the Tc (I) carbonyl
core are considered from the coordination-chemical viewpoint. The coordination behavior of …

This article reviews Re and Tc organometallic chemistry and radiochemistry, focusing on the
most relevant aspects to design radiotools for molecular imaging and therapy. The review …

Vasoactive intestinal peptide receptors (VIPRs) are members of the G-protein-coupled
receptor superfamily. These receptors are overexpressed in many common malignant …

Background/Purpose The VPAC1 receptor, a member of the vasoactive intestinal peptide
receptors (VIPRs), is overexpressed in the most frequently occurring malignant tumors and …

The target of this study is the synthesis of a new diester derivative and radiolabeling with
one of the most effective diagnostic radioisotopes to be investigated as a novel targeting …

Neuropeptides are potentially valuable tools for clinical applications as they offer many
distinct advantages over other bioactive molecules like proteins and monoclonal antibodies …

A novel sulphonamide derivative (EPBS) was prepared at high yield and characterized by 1
H NMR and infrared radiation spectroscopy. Its cytotoxic activity was examined in breast …