Comparison of vitamin D and resveratrol performances in COVID-19

C Russo, MS Valle, L Malaguarnera, IR Romano… - Nutrients, 2023 - mdpi.com
Over the last few years, we have experienced the infection generated by severe respiratory
syndrome coronavirus 2 (SARS-CoV-2) often resulting in an exaggerated immune reaction …

A review on lipid-based nanocarriers mimicking chylomicron and their potential in drug delivery and targeting infectious and cancerous diseases

RE Elnady, MM Amin, MY Zakaria - AAPS Open, 2023 - Springer
Infectious and cancerous diseases are tedious to manage. The problem of drug resistance is
often associated with anti-microbial and anti-cancer agents and is one of the most significant …

Chitosan surface-modified PLGA nanoparticles loaded with cranberry powder extract as a potential oral delivery platform for targeting colon cancer cells

MM Mostafa, MM Amin, MY Zakaria, MA Hussein… - Pharmaceutics, 2023 - mdpi.com
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …

Natural morin-based metal organic framework nanoenzymes modulate articular cavity microenvironment to alleviate osteoarthritis

J Cai, L Liu, Z Qin, S Liu, Y Wang, Z Chen, Y Yao… - Research, 2023 - spj.science.org
Osteoarthritis (OA) is always characterized as excessive reactive oxygen species (ROS)
inside articular cavity. Mimicking natural metalloenzymes with metal ions as the active …

'Poly phenolic phytoceutical loaded nano-bilosomes for enhanced caco-2 cell permeability and SARS-CoV 2 antiviral activity': in-vitro and insilico studies

MY Zakaria, SM Abd El-Halim, BY Beshay, I Zaki… - Drug Delivery, 2023 - Taylor & Francis
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) predisposed to the
emergence of worldwide catastrophe that impels the evolution of safe and effective …

Ultra-deformable free fatty acid based nano-carriers for topical delivery of Luteolin: A potential paradigm for management of Methicillin-Resistant Staphylococcus …

MY Zakaria, WA Eraqi, SA Mohamed - International Journal of …, 2023 - Elsevier
The incidences of antimicrobial resistance in particular, Methicillin-Resistant Staphylococcus
aureus (MRSA) have increased during the last two decades. However, conventional dosage …

Employment of PEGylated ultra-deformable transferosomes for transdermal delivery of tapentadol with boosted bioavailability and analgesic activity in post-surgical …

P Deng, RE Masoud, WM Alamoudi… - International journal of …, 2022 - Elsevier
The utilization of the proper and safe analgesics was considered a major concern in pain
alleviation especially that associated with surgical procedures. Novel analgesics as …

Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in …

AA Al-Karmalawy, DS El-Gamil… - Journal of Enzyme …, 2023 - Taylor & Francis
In this article, emulsomes (EMLs) were fabricated to encapsulate the N-(5-nitrothiazol-2-yl)-
carboxamido derivatives (3a–3g) in an attempt to improve their biological availability and …

Chrysin loaded nanovesicles ameliorated diabetic peripheral neuropathy. Role of NGF/AKT/GSK-3β pathway

SA El-Marasy, MM AbouSamra… - Chemico-Biological …, 2023 - Elsevier
Diabetic peripheral neuropathy (DPN) is a common diabetic complication. Chrysin (CHY)
has many biological properties but poor oral bioavailability. This study investigates the effect …

A micro-configured multiparticulate reconstitutable suspension powder of fixed dose rifampicin and pyrazinamide: optimal fabrication and in vitro quality evaluation

PN Rampedi, MO Ogunrombi, J Wesley-Smith… - Pharmaceutics, 2022 - mdpi.com
The scarcity of age-appropriate pharmaceutical formulations is one of the major challenges
impeding successful management of tuberculosis (TB) prevalence in minors. To this end, we …