CD3+CD4-CD8- (Double-Negative) T Cells in Inflammation, Immune Disorders and Cancer
Z Wu, Y Zheng, J Sheng, Y Han, Y Yang… - Frontiers in …, 2022 - frontiersin.org
The crucial role of CD4+ and CD8+ T cells in shaping and controlling immune responses
during immune disease and cancer development has been well established and used to …
during immune disease and cancer development has been well established and used to …
Tropism of human pegivirus (formerly known as GB virus C/hepatitis G virus) and host immunomodulation: insights into a highly successful viral infection
ET Chivero, JT Stapleton - Journal of General Virology, 2015 - microbiologyresearch.org
Human pegivirus (HPgV; originally called GB virus C/hepatitis G virus) is an RNA virus
within the genus Pegivirus of the family Flaviviridae that commonly causes persistent …
within the genus Pegivirus of the family Flaviviridae that commonly causes persistent …
The Hitchhiker Guide to CD4+ T-Cell Depletion in Lentiviral Infection. A Critical Review of the Dynamics of the CD4+ T Cells in SIV and HIV Infection
Q Le Hingrat, I Sereti, AL Landay, I Pandrea… - Frontiers in …, 2021 - frontiersin.org
CD4+ T-cell depletion is pathognomonic for AIDS in both HIV and simian immunodeficiency
virus (SIV) infections. It occurs early, is massive at mucosal sites, and is not entirely reverted …
virus (SIV) infections. It occurs early, is massive at mucosal sites, and is not entirely reverted …
Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys
Q Le Hingrat, P Sette, C Xu, AR Rahmberg… - Nature …, 2023 - nature.com
CD4+ T-cell depletion is a hallmark of HIV infection, leading to impairment of cellular
immunity and opportunistic infections, but its contribution to SIV/HIV-associated gut …
immunity and opportunistic infections, but its contribution to SIV/HIV-associated gut …
Double negative T regulatory cells: an emerging paradigm shift in reproductive immune tolerance?
EE Bafor, JC Valencia, HA Young - Frontiers in Immunology, 2022 - frontiersin.org
Immune regulation of female reproductive function plays a crucial role in fertility, as
alterations in the relationship between immune and reproductive processes result in …
alterations in the relationship between immune and reproductive processes result in …
Walk on the wild side: SIV infection in African non-human primate hosts—from the field to the laboratory
AJ Jasinska, C Apetrei, I Pandrea - Frontiers in Immunology, 2023 - frontiersin.org
HIV emerged following cross-species transmissions of simian immunodeficiency viruses
(SIVs) that naturally infect non-human primates (NHPs) from Africa. While HIV replication …
(SIVs) that naturally infect non-human primates (NHPs) from Africa. While HIV replication …
HIV Infection and Persistence in Pulmonary Mucosal Double Negative T Cells In Vivo
O Meziane, S Salahuddin, TNQ Pham… - Journal of …, 2020 - Am Soc Microbiol
The lungs are relatively unexplored anatomical human immunodeficiency virus (HIV)
reservoirs in the antiretroviral therapy (ART) era. Double negative (DN) T cells are a subset …
reservoirs in the antiretroviral therapy (ART) era. Double negative (DN) T cells are a subset …
Imprint of unconventional T‐cell response in acute hepatitis C persists despite successful early antiviral treatment
Unconventional T cells (UTCs) are a heterogeneous group of T cells that typically exhibit
rapid responses toward specific antigens from pathogens. Chronic hepatitis C virus (HCV) …
rapid responses toward specific antigens from pathogens. Chronic hepatitis C virus (HCV) …
Distinct CD4−CD8− (Double-Negative) Memory T-Cell Subpopulations Are Associated With Indeterminate and Cardiac Clinical Forms of Chagas Disease
LSA Passos, CC Koh, LMD Magalhães… - Frontiers in …, 2021 - frontiersin.org
CD4− CD8−(double-negative, DN) T cells are critical orchestrators of the cytokine network
associated with the pathogenic inflammatory response in one of the deadliest …
associated with the pathogenic inflammatory response in one of the deadliest …
Lost in translation: lack of CD4 expression due to a novel genetic defect
CD4 expression identifies a subset of mature T cells primarily assisting the germinal center
reaction and contributing to CD8+ T-cell and B-cell activation, functions, and longevity …
reaction and contributing to CD8+ T-cell and B-cell activation, functions, and longevity …