Astrocytes play essential roles in development, homeostasis, injury, and repair of the central
nervous system (CNS). Their development is tightly regulated by distinct spatial and …

Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …

The meninges are a multilayered structure composed of fibroblasts, blood and lymphatic
vessels, and immune cells. Meningeal fibroblasts secrete a variety of factors that control …

Hypertensive cardiac remodeling is accompanied by molecular inflammation and fibrosis, 2
mechanisms that finally affect cardiac function. At cardiac level, aldosterone promotes …

Neurobiological consequences of traumatic brain injury (TBI) result from a complex interplay
of secondary injury responses and sequela that mediates chronic disability. Endothelial cells …

Motivation The reconstruction of small key regulatory networks that explain the differences in
the development of cell (sub) types from single-cell RNA sequencing is a yet unresolved …

N-myristoylation on glycine is an irreversible modification that has long been recognized to
govern protein localization and function. In contrast, the biological roles of lysine …

Perivascular cells expressing platelet-derived growth factor receptor beta (PDGFR-β) have
recently been implicated in fibrotic scar formation after acute brain injury, but their precise …

Fibroblasts are the most common cell type of connective tissues. In the central nervous
system (CNS), fibroblast-like cells are mainly located in the meninges and perivascular …

A kinase anchoring protein (AKAP) 12 is a scaffolding protein that improves the specificity
and efficiency of spatiotemporal signal through assembling intracellular signal proteins into …