Lipids and lipid derivatives for RNA delivery

Y Zhang, C Sun, C Wang, KE Jankovic… - Chemical reviews, 2021 - ACS Publications
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Lipid nanoparticles for drug delivery

L Xu, X Wang, Y Liu, G Yang… - Advanced …, 2022 - Wiley Online Library
Lipid nanoparticles have attracted significant interests in the last two decades, and have
achieved tremendous clinical success since the first clinical approval of Doxil in 1995. At the …

Microfluidic technologies and devices for lipid nanoparticle-based RNA delivery

M Maeki, S Uno, A Niwa, Y Okada, M Tokeshi - Journal of Controlled …, 2022 - Elsevier
In 2021, mRNA vaccines against COVID-19 were approved by the Food and Drug
Administration. mRNA vaccines are important for preventing severe COVID-19 and returning …

[HTML][HTML] Liposomes for tumor targeted therapy: a review

S Wang, Y Chen, J Guo, Q Huang - International journal of molecular …, 2023 - mdpi.com
Liposomes, the most widely studied nano-drug carriers in drug delivery, are sphere-shaped
vesicles consisting of one or more phospholipid bilayers. Compared with traditional drug …

Microfluidic nanoparticles for drug delivery

Y Liu, G Yang, Y Hui, S Ranaweera, CX Zhao - Small, 2022 - Wiley Online Library
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades.
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …

Clinical translation of nanomedicines: Challenges, opportunities, and keys

MA Younis, HM Tawfeek, AAH Abdellatif… - Advanced drug delivery …, 2022 - Elsevier
Despite the massive interest and recent developments in the field of nanomedicine, only a
limited number of formulations have found their way to the clinics. This shortcoming reveals …

Recent advancements in liposome technology

N Filipczak, J Pan, SSK Yalamarty… - Advanced drug delivery …, 2020 - Elsevier
The liposomes have continued to be well-recognized as an important nano-sized drug
delivery system with attractive properties, such a characteristic bilayer structure assembling …

Mussel-inspired chemistry: a promising strategy for natural polysaccharides in biomedical applications

F Liu, X Liu, F Chen, Q Fu - Progress in Polymer Science, 2021 - Elsevier
Polysaccharides are a kind of natural biopolymers and have been widely applied in various
fields, especially biomedical applications, due to their fascinating properties, such as …

[HTML][HTML] Isolation and characterization of exosomes for cancer research

L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021 - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …