Neutrophil interactions with the sexually transmitted parasite Trichomonas vaginalis: implications for immunity and pathogenesis

SB Bhakta, JA Moran, F Mercer - Open biology, 2020 - royalsocietypublishing.org
Trichomoniasis is the third most common sexually transmitted infection in humans and is
caused by the protozoan parasite, Trichomonas vaginalis (Tv). Pathogenic outcomes are …

Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis

MK Tolbert, JL Gookin - Journal of veterinary internal medicine, 2016 - Wiley Online Library
Almost 20 years has passed since trichomonosis was first recognized as a potential cause of
diarrhea in domestic cats. Despite progress in confirming disease causation, developing …

Neutrophils kill the parasite Trichomonas vaginalis using trogocytosis

F Mercer, SH Ng, TM Brown, G Boatman… - PLoS biology, 2018 - journals.plos.org
T. vaginalis, a human-infective parasite, causes the most common nonviral sexually
transmitted infection (STI) worldwide and contributes to adverse inflammatory disorders. The …

Trichomonas vaginalis Lipophosphoglycan Mutants Have Reduced Adherence and Cytotoxicity to Human Ectocervical Cells

FD Bastida-Corcuera, CY Okumura, A Colocoussi… - Eukaryotic …, 2005 - Am Soc Microbiol
The extracellular human pathogen Trichomonas vaginalis is covered by a dense glycocalyx
thought to play a role in host-parasite interactions. The main component of the glycocalyx is …

Production of Interleukin-8 by Human Neutrophils Stimulated with Trichomonas vaginalis

JS Ryu, JH Kang, SY Jung, MH Shin, JM Kim… - Infection and …, 2004 - Am Soc Microbiol
Neutrophils are the predominant inflammatory cells found in the vaginal discharges of
patients infected with Trichomonas vaginalis. Although chemoattractants, such as …

Molecular Identification of Tritrichomonas foetus-Like Organisms as Coinfecting Agents of Human Pneumocystis Pneumonia

C Duboucher, S Caby, F Dufernez… - Journal of Clinical …, 2006 - Am Soc Microbiol
Trichomonads closely related to the bovid parasite Tritrichomonas foetus were identified in
the bronchoalveolar lavage sample from a patient with AIDS in association with …

Correlation of leukorrhea and Trichomonas vaginalis infection

GB Lazenby, DE Soper, FS Nolte - Journal of clinical microbiology, 2013 - Am Soc Microbiol
Trichomonas vaginalis is a common sexually transmitted infection (STI) causing vaginitis.
Microscopy has poor sensitivity but is used for diagnosis of trichomoniasis in resource-poor …

[HTML][HTML] Trichomonas vaginalis inhibits proinflammatory cytokine production in macrophages by suppressing NF-κB activation

JH Chang, YS Ryang, T Morio, SK Lee, EJ Chang - Molecules and cells, 2004 - Elsevier
Activation of NF-κB leads to the production of proinflammatory cytokines such as IL-12 and
TNF-α that are involved in innate and adaptive immunity. We determined whether T …

Trichomonas vaginalis nucleoside triphosphate diphosphohydrolase and ecto-5′-nucleotidase activities are inhibited by lycorine and candimine

RB Giordani, M Weizenmann, DB Rosemberg… - Parasitology …, 2010 - Elsevier
Drug discovery from plants plays an important role in the pharmaceutical therapy field and
the alkaloids lycorine and candimine are candidates for this purpose. Trichomonas vaginalis …

Trichomonas vaginalis promotes apoptosis of human neutrophils by activating caspase‐3 and reducing Mcl‐1 expression

JH Kang, HO Song, JS Ryu, MH Shin… - Parasite …, 2006 - Wiley Online Library
Neutrophils are the predominant inflammatory cells found in the vaginal discharge of
patients with Trichomonas vaginalis infection. However, it is not known whether neutrophil …