[HTML][HTML] MRI-based parameter inference for cerebral perfusion modelling in health and ischaemic stroke

TI Józsa, J Petr, SJ Payne, HJMM Mutsaerts - Computers in Biology and …, 2023 - Elsevier
Cerebral perfusion modelling is a promising tool to predict the impact of acute ischaemic
stroke treatments on the spatial distribution of cerebral blood flow (CBF) in the human brain …

[HTML][HTML] In silico trials for treatment of acute ischemic stroke: design and implementation

C Miller, RM Padmos, M van der Kolk, TI Józsa… - Computers in biology …, 2021 - Elsevier
An in silico trial simulates a disease and its corresponding therapies on a cohort of virtual
patients to support the development and evaluation of medical devices, drugs, and …

A collateral circulation in ischemic stroke accelerates recanalization due to lower clot compaction

S Thalerová, A Vítečková Wünschová, P Kittová… - PloS one, 2024 - journals.plos.org
Collaterals improve recanalization in acute ischemic stroke patients treated with intravenous
thrombolysis, but the mechanisms are poorly understood. To investigate it, an in vitro flow …

Effect of vascular compression and drug injection time on thrombolytic therapy: Numerical simulation and validation

H Zhou, H Cheng, B Lin, S Li, X Zhang - Journal of Biomechanics, 2024 - Elsevier
Venous thromboembolism (VTE) has been occurring frequently in human society. There is
an urgent need to study the influence of several factors on thrombolytic therapy, such as the …

A simplified mesoscale 3D model for characterizing fibrinolysis under flow conditions

R Petkantchin, A Rousseau, O Eker… - Scientific reports, 2023 - nature.com
One of the routine clinical treatments to eliminate ischemic stroke thrombi is injecting a
biochemical product into the patient's bloodstream, which breaks down the thrombi's fibrin …

MRI-based computational model generation for cerebral perfusion simulations in health and ischaemic stroke

TI Józsa, J Petr, F Barkhof, SJ Payne, H Mutsaerts - bioRxiv, 2022 - biorxiv.org
Cerebral perfusion models were found to be promising research tools to predict the impact
of acute ischaemic stroke and related treatments on cerebral blood flow (CBF) linked to …

[PDF][PDF] Thrombus mechanics: How can we contribute to improve diagnostics and treatment?

F Migliavacca, G Luraghi, AC Akyildiz… - Journal of …, 2022 - re.public.polimi.it
Treatment of acute ischemic stroke (AIS) has gained interest in the recent years with the
introduction, first of intravenous administration of thrombus-dissolving drugs, and more …

[PDF][PDF] In-vitro Evaluation of Antithrombin and Thrombolytic Activity of Leaves Extract of Lantana camara Linn

S Mujbaile, D Khobragade, D Mundhada - academia.edu
Thrombosis is possible outcomes of excessive coagulation or inhibition of anticoagulant
processes. The pathophysiology of thrombosis is primarily caused by irregularities of the …