Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

There are declines with age in speed of processing, working memory, inhibitory function,
and long-term memory, as well as decreases in brain structure size and white matter …

A model of the effects of aging on brain activity during cognitive performance is introduced.
The model is called HAROLD (hemispheric asymmetry reduction in older adults), and it …

To develop targeted intervention strategies for the treatment of Alzheimer's disease, we first
need to identify early markers of brain changes that occur before the onset of cognitive …

Frontal contributions to cognitive decline in aging were explored using functional MRI.
Frontal regions active in younger adults during self-initiated (intentional) memory encoding …

Over the years, a large body of literature has shown that humans display losses in memory
with age, but that not all types of memory are affected equally. Similarly, recent evidence …

This article addresses key topics in cognitive aging, intending to provide the reader with a
brief overview of the current state of research in this growing, multidisciplinary field. A …

This review article surveys the evidence for age-related changes in memory from cognitive
and neuroimaging studies. It is probable that the observed declines in episodic memory with …

A number of theories have emerged to explain the well-studied changes in memory that
occur with age. Many of these theories invoke mechanisms that have the potential to affect …

Objectives This review focuses on the relationship between obesity and aging and how
these interact to affect cognitive function. The topics covered are guided by the Scaffolding …