Rhabdomyosarcoma

SX Skapek, A Ferrari, AA Gupta, PJ Lupo… - Nature reviews disease …, 2019 - nature.com
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and
represents a high-grade neoplasm of skeletal myoblast-like cells. Decades of clinical and …

An update on rhabdomyosarcoma risk stratification and the rationale for current and future Children's Oncology Group clinical trials

JH Haduong, CM Heske… - Pediatric blood & …, 2022 - Wiley Online Library
Children and adolescents with rhabdomyosarcoma (RMS) comprise a heterogeneous
population with variable overall survival rates ranging between approximately 6% and 100 …

Rhabdomyosarcoma: current therapy, challenges, and future approaches to treatment strategies

A Zarrabi, D Perrin, M Kavoosi, M Sommer, S Sezen… - Cancers, 2023 - mdpi.com
Simple Summary Rhabdomyosarcoma (RMS) is a rare pediatric sarcoma affecting skeletal
muscle in children and young adults. It is responsible for 3% of all childhood malignant …

Cinnamon cassia oil chitosan nanoparticles: Physicochemical properties and anti-breast cancer activity

X Xu, Q Li, W Dong, G Zhao, Y Lu, X Huang… - International Journal of …, 2023 - Elsevier
The aim of this study was to prepare Cinnamomum cassia essential oil (CEO) impregnated
chitosan nanoparticles (CS-CEO) and assess its pharmacological activity against breast …

Randomized phase II trial of bevacizumab or temsirolimus in combination with chemotherapy for first relapse rhabdomyosarcoma: a report from the Children's …

L Mascarenhas, YY Chi, P Hingorani… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE The primary aim of this clinical trial was to prioritize bevacizumab or temsirolimus
for additional investigation in rhabdomyosarcoma (RMS) when administered in combination …

Soft tissue sarcomas in adolescents and young adults

AR Weiss, DJ Harrison - Journal of Clinical Oncology, 2024 - ascopubs.org
Soft tissue sarcomas (STS) represent a heterogeneous group of extraskeletal mesenchymal
tumors that affect individuals throughout the entire age continuum. Despite this pervasive …

Increased local failure for patients with intermediate‐risk rhabdomyosarcoma on ARST0531: a report from the Children's Oncology Group

DL Casey, YY Chi, SS Donaldson, DS Hawkins… - Cancer, 2019 - Wiley Online Library
Background The objective of this study was to evaluate local control for patients with
intermediate‐risk rhabdomyosarcoma (RMS) treated on Children's Oncology Group (COG) …

Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup

FKF Kommoss, D Stichel, J Mora, M Esteller… - Modern …, 2021 - nature.com
Embryonal rhabdomyosarcoma (ERMS) of the uterus has recently been shown to frequently
harbor DICER1 mutations. Interestingly, only rare cases of extrauterine DICER1-associated …

Pathogenic germline variants in cancer susceptibility genes in children and young adults with rhabdomyosarcoma

J Kim, N Light, V Subasri, EL Young… - JCO Precision …, 2021 - ascopubs.org
PURPOSE Rhabdomyosarcoma (RMS) is the most common pediatric soft-tissue sarcoma
and accounts for 3% of all pediatric cancer. In this study, we investigated germline sequence …

Recent advances and challenges in the treatment of rhabdomyosarcoma

S Miwa, N Yamamoto, K Hayashi, A Takeuchi… - Cancers, 2020 - mdpi.com
Rhabdomyosarcoma, the most common soft tissue sarcoma noted in childhood, requires
multimodality treatment, including chemotherapy, surgical resection, and/or radiation …