Carboranes in drug discovery, chemical biology and molecular imaging

A Marfavi, P Kavianpour, LM Rendina - Nature Reviews Chemistry, 2022 - nature.com
There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …

Multi-functional boron-delivery agents for boron neutron capture therapy of cancers

SO Oloo, KM Smith, MGH Vicente - Cancers, 2023 - mdpi.com
Simple Summary Many boron-containing compounds have been synthesized and proposed
as boron-delivery agents for boron neutron capture therapy for cancers, including brain …

Polymer-stabilized elemental boron nanoparticles for boron neutron capture therapy: Initial irradiation experiments

A Zaboronok, P Khaptakhanova, S Uspenskii… - Pharmaceutics, 2022 - mdpi.com
Sufficient boron-10 isotope (10B) accumulation by tumor cells is one of the main
requirements for successful boron neutron capture therapy (BNCT). The inability of the …

Experimental synthesis, functionalized modifications and potential applications of monoelemental zero-dimensional boron nanomaterials

M Yang, H Jin, Z Sun, R Gui - Journal of Materials Chemistry A, 2022 - pubs.rsc.org
The past decade has witnessed a rapid growth in scientific studies on zero-dimensional (0D)
boron nanomaterials, mainly involving boron nanoparticles, boron quantum dots, boron …

Boron clusters as enhancers of RNase H activity in the smart strategy of gene silencing by antisense oligonucleotides

D Kaniowski, K Kulik, J Suwara… - International Journal of …, 2022 - mdpi.com
Boron cluster-conjugated antisense oligonucleotides (B-ASOs) have already been
developed as therapeutic agents with “two faces”, namely as potential antisense inhibitors of …

EGFR-targeted cellular delivery of therapeutic nucleic acids mediated by boron clusters

D Kaniowski, J Suwara, K Ebenryter-Olbińska… - International Journal of …, 2022 - mdpi.com
New boron carriers with high boron content and targeted cancer-cell delivery are considered
the first choice for boron neutron capture therapy (BNCT) for cancer treatment. Previously …

The impact of metal nanoparticles on female reproductive system: risks and opportunities

M Aloisi, G Rossi, S Colafarina, M Guido… - International journal of …, 2022 - mdpi.com
Humans have always been exposed to tiny particles via dust storms, volcanic ash, and other
natural processes, and our bodily systems are well adapted to protect us from these …

Synthesis of DNA‐Boron Cluster Composites and Assembly into Functional Nanoparticles with Dual, Anti‐EGFR, and Anti‐c‐MYC Oncogene Silencing Activity

K Bednarska‐Szczepaniak… - … A European Journal, 2024 - Wiley Online Library
A versatile method for the automated synthesis of composites containing DNA‐
oligonucleotides and boron cluster scaffolds and their assembly into functional …

[PDF][PDF] Vicente, MdGH Multi-Functional Boron-Delivery Agents for Boron Neutron Capture Therapy of Cancers. Cancers 2023, 15, 3277. htps

SO Oloo, KM Smith - … Academic Editors: Eiichi Ishikawa, Rolf F …, 2023 - researchgate.net
Boron neutron capture therapy (BNCT) is a binary cancer treatment that involves the
irradiation of 10B-containing tumors with low-energy neutrons (thermal or epithermal). The …