Highlights•Radial glia provide the physical scaffolding and chemical signals to support BBB
formation.•Early astrocyte development relies on mechanical and chemical cues from …

This review will focus on early aspects of cortical interneurons (cIN) development from
specification to migration and final positioning in the human cerebral cortex. These …

The development of stable specialized cell types in multicellular organisms relies on
mechanisms controlling inductive intercellular signals and the competence of cells to …

In human telencephalon at 8–12 postconceptional weeks, ribonucleic acid quantitative
sequencing and immunohistochemistry revealed cortical chicken ovalbumin upstream …

Abstract The Sonic hedgehog (SHh) signaling pathway is an imperative operating network
that helps in regulates the critical events during the development processes like multicellular …

Evolutionary elaboration of tissues starts with changes in the genome and location of the
stem cells. For example, GABAergic interneurons of the mammalian neocortex are …

Abstract Development of vertebrate nervous system is a complex process which involves
differential gene expression and disruptions in this process or in the mature brain, may lead …

N-methyl d-aspartate receptors (NMDARs), a subtype of glutamate receptor, have important
functional roles in cellular activity and neuronal development. They are well-studied in …

The cerebral cortex functions by the complex interactions of intrinsic and extrinsic neuronal
activities, glial actions, and the effects of humoral factors. The intrinsic neuronal influences …

Abstract Sonic Hedgehog (Shh) plays an instrumental role in brain development, fine-tuning
processes such as cell proliferation, patterning, and fate specification. Although, mutations in …