Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

G El-Saber Batiha, A Magdy Beshbishy, L G. Wasef… - Nutrients, 2020 - mdpi.com
Medicinal plants have been used from ancient times for human healthcare as in the form of
traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an …

Reactive oxygen species in osteoclast differentiation and possible pharmaceutical targets of ROS-mediated osteoclast diseases

TS Agidigbi, C Kim - International journal of molecular sciences, 2019 - mdpi.com
Reactive oxygen species (ROS) and free radicals are essential for transmission of cell
signals and other physiological functions. However, excessive amounts of ROS can cause …

Natural medicinal compounds in bone tissue engineering

S Bose, N Sarkar - Trends in biotechnology, 2020 - cell.com
Recent advances in 3D printing have provided unprecedented opportunities in bone tissue
engineering applications for producing a variety of complex patient-specific implants for the …

A Critical Review on the Nutritional and Medicinal Profiles of Garlic's (Allium sativum L.) Bioactive Compounds

MA Ozma, A Abbasi… - Food Reviews …, 2023 - Taylor & Francis
The medicinal characteristics of garlic's (Allium sativum L.) dynamically bioactive
constituents such as alliin, allicin, ajoene, S-allyl-cysteine, S-trityl-L-cysteine, diallyl sulfide …

[HTML][HTML] The ethnobotanical, bioactive compounds, pharmacological activities and toxicological evaluation of garlic (Allium sativum): A review

BC Okoro, TM Dokunmu, E Okafor, IA Sokoya… - Pharmacological …, 2023 - Elsevier
Abstract Background Garlic (Allium sativum) is a medicinal plant exploited for its diverse
pharmacological benefits and used as a cooking spice globally. In traditional Chinese …

Alliin alleviates LPS-induced pyroptosis via promoting mitophagy in THP-1 macrophages and mice

M Liu, J Lu, S Yang, Y Chen, J Yu, S Guan - Food and Chemical Toxicology, 2022 - Elsevier
Pyroptosis is a new type of programmed cell death associated with inflammation. Excessive
pyroptosis can cause body damage. Alliin is an organosulfur compound extracted from …

Targeting reactive oxygen species in stem cells for bone therapy

X Li, B Li, Y Shi, C Wang, L Ye - Drug Discovery Today, 2021 - Elsevier
Highlights•ROS critically regulate the fate and function of stem cells from non-hematopoietic
and hematopoietic lineage to control bone hemostasis.•Excessive ROS accumulation in …

Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo

C Cai, C Liu, L Zhao, H Liu, W Li, H Guan… - Frontiers in …, 2018 - frontiersin.org
Osteoporosis is a highly prevalent disease which has been a major public health problem
and considered to be associated with chronic low-grade systemic inflammation and …

[HTML][HTML] Liraglutide, a glucagon-like peptide-1 receptor agonist, suppresses osteoclastogenesis through the inhibition of NF-κB and MAPK pathways via GLP-1R

Z Li, S Li, N Wang, P Xue, Y Li - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Bone disorders such as osteoporosis, Paget's disease of the bone, osteogenesis imperfecta,
are caused by the uncoordinated action of osteoclasts and osteoblasts. Inhibiting …

Antitumor Effects of Natural Compounds Derived from Allium sativum on Neuroblastoma: An Overview

CC Patiño-Morales, R Jaime-Cruz, C Sánchez-Gómez… - Antioxidants, 2021 - mdpi.com
Garlic (Allium sativum) has been used in alternative medicine to treat several diseases, such
as cardiovascular and neurodegenerative diseases, cancer, and hepatic diseases. Several …