OBJECTIVES Early-stage lung adenocarcinoma (ADC) has a great heterogeneity in
prognosis that is difficult to evaluate effectively. Thus, we developed and validated an …

Background Coagulation disorders are a significant cause of lung cancer mortality. Although
mast cells are known to play a role in coagulation abnormalities, their specific role in this …

Simple Summary Non-small cell lung cancer (NSCLC) is a common diagnosis from which
many patients die. Blood tests reflecting systemic inflammation are routinely collected in the …

Tissue factor (TF) is an integral transmembrane protein associated with the extrinsic
coagulation pathway. TF gene expression is regulated in response to inflammatory …

Podoplanin (PDPN) is known to play a role in thrombosis, metastasis of tumor cells, the
epithelial–mesenchymal transition (EMT), and immune response. The present study aim to …

Background This study aimed to establish a nomogram to distinguish advanced-and early-
stage lung cancer based on coagulation-related biomarkers and liver-related biomarkers …

Background The acid glycoprotein 1 (AGP1) is downregulated in lung cancer. However, the
performance of AGP1 in distinguishing benign from malignant lung lesions is still unknown …

Introduction: This study on lung adenocarcinoma (LUAD), a common lung cancer subtype
with high mortality. Aims: This study focuses on how tumor cell interactions affect …

出凝血功能异常是恶性肿瘤发生, 发展的重要特征. 肿瘤细胞释放促血管生成因子引起血管内皮
损伤, 并诱导血小板活化和增多, 均增加了血栓形成的风险. 肿瘤患者常表现为活化部分凝血活酶 …

The prognosis of advanced lung adenocarcinoma (LUAD) remains unfavorable, with
chemotherapy constituting a primary treatment modality. Discerning the efficacy of …