Over the past 40 years, the prevalence of obesity has increased epidemically worldwide,
which raises significant concerns regarding public health and the associated economic …

Prostate cancer is uniquely dependent on androgens. Despite years of research on the
relationship between androgens and prostate cancer, many questions remain as to the …

Objectives To evaluate the effects of testosterone‐replacement therapy (TRT) on prostate
health indicators in hypogonadal men, including rates of prostate cancer diagnoses …

Purpose The association between exposure to testosterone replacement therapy (TRT) and
prostate cancer risk is controversial. The objective was to examine this association through …

Background There has been concern about the growing off-label use of testosterone.
Understanding the context within which testosterone is prescribed may contribute to …

The diagnostic specificity of prostate specific antigen (PSA) is limited. We aimed to
characterize eight anti-PSA monoclonal antibodies (mAbs) to assess the prostate cancer …

Objectives To develop and validate a risk calculator for prostate cancer (PCa) and clinically
significant PCa (csPCa) using explainable artificial intelligence (XAI). Patients and Methods …

Background Fat distribution varies between individuals of similar body mass index (BMI). We
hypothesized that visceral obesity is more strongly associated with poor prostate cancer …

This study investigated the role of testosterone replacement therapy (TRT) in prostate safety
and cancer progression. A cohort of 553 patients, 42 treated and 162 untreated …

Background Testosterone deficiency (TD) may induce a series of clinical symptoms. Studies
have shown that testosterone supplementation may prevent these unfavourable symptoms …