Risk score generated from CT-based radiomics signatures for overall survival prediction in non-small cell lung cancer

VH Le, QH Kha, TNK Hung, NQK Le - Cancers, 2021 - mdpi.com
Simple Summary Despite recent advancements in lung cancer treatment, individuals with
lung cancer have a dismal 5-year survival rate of only 15%. In patients with non-small cell …

Computational resources in healthcare

N Sharma, LD Naorem, S Gupta… - … Reviews: Data Mining …, 2022 - Wiley Online Library
Healthcare is the most important component in the life of all human beings as each
individual wish to have happy, healthy, and wealthy life‐span. Most of the branches of …

Microbial genotoxin-elicited host DNA mutations related to mitochondrial dysfunction, a momentous contributor for colorectal carcinogenesis

X Yang, Y Gan, Y Zhang, Z Liu, J Geng, W Wang - Msystems, 2024 - journals.asm.org
Gut microbe dysbiosis increases repetitive inflammatory responses, leading to an increase
in the incidence of colorectal cancer. Recent studies have revealed that specific microbial …

MCL1 nuclear translocation induces chemoresistance in colorectal carcinoma

D Fu, L Pfannenstiel, A Demelash, YP Phoon… - Cell Death & …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most common and deadliest forms of cancer. Myeloid
Cell Leukemia 1 (MCL1), a pro-survival member of the Bcl-2 protein family is associated with …

CancerLivER: a database of liver cancer gene expression resources and biomarkers

H Kaur, S Bhalla, D Kaur, GPS Raghava - Database, 2020 - academic.oup.com
Liver cancer is the fourth major lethal malignancy worldwide. To understand the
development and progression of liver cancer, biomedical research generated a tremendous …

Prognostic biomarkers for predicting papillary thyroid carcinoma patients at high risk using nine genes of apoptotic pathway

C Arora, D Kaur, LD Naorem, GPS Raghava - PLoS One, 2021 - journals.plos.org
Aberrant expressions of apoptotic genes have been associated with papillary thyroid
carcinoma (PTC) in the past, however, their prognostic role and utility as biomarkers remains …

In silico model for predicting IL-2 inducing peptides in human

A Lathwal, R Kumar, D kaur, GPS Raghava - bioRxiv, 2021 - biorxiv.org
Abstract Interleukin-2 (IL-2) based immunotherapy has been already approved to treat
certain type of cancers as it plays vital role in immune system. Thus it is important to discover …

Identification of prognostic biomarkers for major subtypes of non-small-cell lung cancer using genomic and clinical data

A Lathwal, R Kumar, C Arora, GPS Raghava - Journal of Cancer Research …, 2020 - Springer
Purpose Intra-tumor heterogeneity and high mortality among patients with non-small-cell
lung carcinoma (NSCLC) emphasize the need to identify reliable prognostic markers unique …

Prognostic model and nomogram for estimating survival of small breast cancer: A SEER-based analysis

Y Han, J Wang, Y Sun, P Yu, P Yuan, F Ma, Y Fan… - Clinical Breast …, 2021 - Elsevier
Background Different clinicopathologic characteristics could contribute to inconsistent
prognoses of small breast neoplasms (T1a/T1b). This study was done to conduct a …

Risk prediction in cutaneous melanoma patients from their clinico-pathological features: superiority of clinical data over gene expression data

C Arora, D Kaur, A Lathwal, GPS Raghava - Heliyon, 2020 - cell.com
Risk assessment in cutaneous melanoma (CM) patients is one of the major challenges in
the effective treatment of CM patients. Traditionally, clinico-pathological features such as …