Background Alzheimer's disease (AD) is the most prevalent form of dementia worldwide and
is characterized by progressive memory loss and cognitive impairment. Our understanding …

Autophagy involves the sequestration and delivery of cytoplasmic materials to lysosomes,
where proteins, lipids, and organelles are degraded and recycled. According to the way the …

Background: Mitophagy is correlated with tumor initiation and development of malignancy.
However, HCC heterogeneity with reference to mitophagy has yet not been systematically …

Introduction Alzheimer's disease (AD) is a common neurodegenerative disease. The
concealment of the disease is the difficulty of its prevention and treatment. Previous studies …

Alzheimer's and Parkinson's diseases are two of the most frequent neurological diseases.
The clinical features of AD are memory decline and cognitive dysfunction, while PD mainly …

Self-expressiveness is a mathematical property that aims at characterizing the relationship
between instances in a dataset. This property has been applied widely and successfully in …

The brain is, after the adipose tissue, the organ with the greatest amount of lipids and
diversity in their composition in the human body. In neurons, lipids are involved in signaling …

Aluminum (Al) is a food pollutant that has extensive deleterious effects on the liver. Our
previous research proposed that E3 ubiquitin ligase PARK2 knockout (Parkin−/-) could …

Objective. Chronic stress (CS)-induced abnormal metabolism and other subsequent aspects
of abnormality are threatening human health. Little is known regarding whether and how …

Mitochondria play a crucial role in expediting the energy homeostasis under varying
environmental conditions. As mitochondria are controllers of both energy production and …