Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

Harnessing type I IFN immunity against SARS-CoV-2 with early administration of IFN-β

DC Vinh, L Abel, P Bastard, MP Cheng… - Journal of clinical …, 2021 - Springer
Since December 2019, over 150 million individuals have been infected with SARS-CoV-2
globally. While most cases (> 95%) are asymptomatic or mild, a small proportion develop …

RETRACTED: Clinical and Scientific Rationale for the “MATH+” Hospital Treatment Protocol for COVID-19

P Kory, GU Meduri, J Iglesias… - Journal of Intensive …, 2021 - journals.sagepub.com
Abstract In December 2019, COVID-19, a severe respiratory illness caused by the new
coronavirus SARS-CoV-2 (COVID-19) emerged in Wuhan, China. The greatest impact that …

Синдром диссеминированного внутрисосудистого свертывания крови при инфекции COVID-19

ПА Воробьев, АП Момот, АА Зайцев, ВА Елыкомов… - Терапия, 2020 - elibrary.ru
В работе приводится методология разработки научно-обоснованных рекомендаций по
диагностике и терапии синдрома диссеминированного внутри со суд и сто го …

The “sex gap” in COVID-19 trials: A scoping review

VMMM Schiffer, EBNJ Janssen, BCT van Bussel… - …, 2020 - thelancet.com
Background Many studies investigate the role of pharmacological treatments on disease
course in Corona Virus Disease 2019 (COVID-19). Sex disparities in genetics …

Algorithm for the diagnosis and management of the multisystem inflammatory syndrome in children associated with COVID‐19

S Emeksiz, B Çelikel Acar, AE Kibar… - … Journal of Clinical …, 2021 - Wiley Online Library
Objective Although the initial reports of COVID‐19 cases in children described that children
were largely protected from severe manifestations, clusters of paediatric cases of severe …

COVID-19 sepsis: pathogenesis and endothelial molecular mechanisms based on “two-path unifying theory” of hemostasis and endotheliopathy-associated vascular …

JC Chang - Vascular Health and Risk Management, 2021 - Taylor & Francis
COVID-19 sepsis is characterized by acute respiratory distress syndrome (ARDS) as a
consequence of pulmonary tropism of the virus and endothelial heterogeneity of the host …

[HTML][HTML] Role of therapeutic plasma exchange in the management of COVID-19-induced cytokine storm syndrome

M Beraud, S Al Hashami, M Lozano, A Bah… - … and Apheresis Science, 2022 - Elsevier
The risk of mortality in patients with coronavirus disease 2019 (COVID-19) is largely related
to an excessive immune response, resulting in a hyperinflammatory and hypercoagulable …

Understanding the role of therapeutic plasma exchange in COVID‐19: preliminary guidance and practices

GK Patidar, KJ Land, H Vrielink… - Vox …, 2021 - Wiley Online Library
Background and objectives Cytokine release syndrome in COVID‐19 is due to a
pathological inflammatory response of raised cytokines. Removal of these cytokines by …