Wound healing is the physiologic response to tissue trauma proceeding as a complex
pathway of biochemical reactions and cellular events, secreted growth factors, and …

Glycosaminoglycans are natural heteropolysaccharides that are present in every
mammalian tissue. They are composed of repeating disaccharide units that consist of either …

Glycosaminoglycans (GAGs) as one major part of the glycocalyx are involved in many
essential biological cell processes, as well as in many courses of diseases. Because of the …

Sulodexide (SDX), a sulfated polysaccharide complex extracted from porcine intestinal
mucosa, is a blend of two glycosaminoglycan (GAG) entities, namely a fast-moving heparin …

Fibroblast Growth Factor (FGF) signaling plays crucial roles in multiple cellular processes
including cell proliferation, differentiation, survival, and migration during mammalian …

Heparan sulfate (HS) and heparin (Hp) are linear polysaccharide chains composed of
repeating (1→ 4) linked pyrosulfuric acid and 2‐amino‐2‐deoxy glucopyranose …

In recent decades, heparin, as the most important anticoagulant drug, has been widely used
in clinical settings to prevent and treat thrombosis in a variety of diseases. However, with in …

Glycocalyx dysfunction is believed as the first step in diabetic vascular disease. However,
few studies have systematically investigated the influence of HG on the glycocalyx as a …

Acute pancreatitis (AP) is acute inflammation of the pancreas, mainly caused by gallstones
and alcohol, driven by changes in communication between cells. Heparin-binding proteins …

Low molecular weight heparin is a Heparin derivative, produced from commercial-grade
Heparin through Chemical or enzymatic depolymerization. LMWH has remained a favored …