Depending on their tissue of origin, genetic and epigenetic marks and microenvironmental
influences, cancer cells cover a broad range of metabolic activities that fluctuate over time …

Tunneling nanotubes (TNTs) represent a subset of F-actin-based transient tubular
connections that allow direct communication between distant cells. Recent studies have …

In addition to the HLA locus, six genetic risk factors for primary biliary cirrhosis (PBC) have
been identified in recent genome-wide association studies (GWAS). To identify additional …

Mitochondria (MT) participate in most metabolic activities of mammalian cells. A near-
unidirectional mitochondrial transfer from T cells to cancer cells was recently observed to" …

Cell–cell communication is essential for the development and homeostasis of multicellular
organisms. Recently, a new type of cell–cell communication was discovered that is based on …

Alterations in transcription, RNA editing, translation, protein processing, and clearance are a
consistent feature of Alzheimer's disease (AD) brain. To extend our initial study (Alzheimer …

A20 was first identified as a tumor necrosis factor (TNF) primary response transcript
encoding a 790-amino acid protein with a unique zinc finger motif. Recently, A20 was shown …

Podocyte injury leading to albuminuria is a characteristic feature of diabetic nephropathy
(DN). Hyperglycemia and advanced glycation end products (AGEs) are major determinants …

CD95 (Fas/APO-1) and tumor necrosis factor receptor-1 (TNFR-1) are related molecules that
signal apoptosis. Recently, a number of novel binding proteins have been proposed to …

Eph receptor tyrosine kinases and their ephrin ligands have been implicated in embryonic
vascular development and in in vivo models of angiogenesis. Eph proteins may also …